Phase 1b study of pan‐AKT inhibitor vevorisertib alone or with paclitaxel or fulvestrant...

[PDF] mdpi.com

Molecular Targeting of the Phosphoinositide-3-Protein Kinase (PI3K) Pathway across Various Cancers

KS Shan, A Bonano-Rios, NWY Theik… - International Journal of …, 2024 - mdpi.com
The dysregulation of the phosphatidylinositol-3-kinase (PI3K) pathway can lead to
uncontrolled cellular growth and tumorigenesis. Targeting PI3K and its downstream …
被引用次数：2 相关文章 所有 8 个版本

Akt Inhibitor Advancements: From Capivasertib Approval to Covalent-Allosteric Promises

KA Pervanidis, GD D'Angelo, J Weisner… - Journal of Medicinal …, 2024 - ACS Publications
Akt kinase is vital in cell growth, survival, metabolism, and migration. Dysregulation of Akt
signaling is implicated in cancer and metabolic disorders. In the context of cancer …
相关文章 所有 4 个版本