Scientists have been trying to identify every gene in the human genome since the initial draft
was published in 2001. In the years since, much progress has been made in identifying …

Myeloid-derived suppressor cells (MDSCs) expand during pathological conditions in both
humans and mice and their presence is linked to poor clinical outcomes for cancer patients …

Single-cell RNA sequencing (scRNA-seq) is a widely used method for identifying cell types
and trajectories in biologically heterogeneous samples, but it is limited in its detection and …

Multiple studies have demonstrated that diffuse large B-cell lymphoma (DLBCL) can be
divided into subgroups based on their biology; however, these biological subgroups overlap …

Cutaneous T-cell lymphomas are a heterogeneous group of neoplasms originating in the
skin, with mycosis fungoides (MF) and Sézary syndrome (SS) representing the most …

Background: Heart development relies on tight spatiotemporal control of cardiac gene
expression. Genes involved in this intricate process have been identified using animals and …

Advances in next-generation sequencing technology have identified many genes
responsible for inborn errors of immunity (IEI). However, there is still room for improvement …

Diabetes mellitus (DM) is a metabolic disease that heightens the risks of many vascular
complications, including peripheral arterial disease (PAD). Various types of cells, including …

New technologies in genetic diagnostics have revolutionized the understanding and
management of rare diseases. This review highlights the significant advances and latest …

Germline DNA testing using the next-generation sequencing (NGS) technology has become
the analytical standard for the diagnostics of hereditary diseases, including cancer. Its …