The Global Initiative for Asthma (GINA) Strategy Report provides clinicians with an annually
updated evidence-based strategy for asthma management and prevention, which can be …

Severe covid-19 pneumonia has posed critical challenges for the research and medical
communities. Older age, male sex, and comorbidities increase the risk for severe disease …

Background Invasive mechanical ventilation in critically ill adults involves adjusting the
fraction of inspired oxygen to maintain arterial oxygen saturation. The oxygen-saturation …

Background The novel severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) is
the cause of a rapidly spreading illness, Coronavirus Disease 2019 (COVID-19), affecting …

Background In patients with acute respiratory distress syndrome (ARDS), the National Heart,
Lung, and Blood Institute ARDS Clinical Trials Network recommends a target partial …

Mitochondrial structures were probably observed microscopically in the 1840s, but the idea
of oxidative phosphorylation (OXPHOS) within mitochondria did not appear until the 1930s …

Lung diseases have high mortality and morbidity, with an important impact on quality of life.
Hypoxemic patients are advised to use oxygen therapy to prolong their survival, but high …

In December 2019, a novel coronavirus causing severe acute respiratory disease occurred
in Wuhan, China. It is an emerging infectious disease with widespread and rapid …

Rationale: Supplemental oxygen is widely administered to ICU patients, but appropriate
oxygenation targets remain unclear. Objectives: This study aimed to determine whether a …

Oxygen is the most commonly used therapy in hospitalized patients with COVID-19. In those
patients who develop worsening pneumonia and acute respiratory distress syndrome …