Biological Versus Chronological Aging: JACC Focus Seminar

MR Hamczyk, RM Nevado, A Barettino, V Fuster… - Journal of the American …, 2020 - jacc.org
Aging is the main risk factor for vascular disease and ensuing cardiovascular and
cerebrovascular events, the leading causes of death worldwide. In a progressively aging …

Nanomedicines for cardiovascular disease

BR Smith, ER Edelman - Nature Cardiovascular Research, 2023 - nature.com
The leading cause of death in the world, cardiovascular disease (CVD), remains a
formidable condition for researchers, clinicians and patients alike. CVD comprises a broad …

Prevalence of subclinical coronary artery atherosclerosis in the general population

G Bergström, M Persson, M Adiels, E Björnson… - Circulation, 2021 - Am Heart Assoc
Background: Early detection of coronary atherosclerosis using coronary computed
tomography angiography (CCTA), in addition to coronary artery calcification (CAC) scoring …

Intravascular lithotripsy for treatment of severely calcified coronary artery disease

JM Hill, DJ Kereiakes, RA Shlofmitz, AJ Klein… - Journal of the American …, 2020 - jacc.org
Background Coronary calcification hinders stent delivery and expansion and is associated
with adverse outcomes. Intravascular lithotripsy (IVL) delivers acoustic pressure waves to …

Intravascular Lithotripsy for Vessel Preparation in Severely Calcified Coronary Arteries Prior to Stent Placement―Primary Outcomes From the Japanese Disrupt CAD …

S Saito, S Yamazaki, A Takahashi, A Namiki… - Circulation …, 2021 - jstage.jst.go.jp
Background: Intravascular lithotripsy (IVL) delivers acoustic pressure waves to modify
calcium, enhance vessel compliance and optimize stent deployment. The objective of this …

Nicotine promotes vascular calcification via intracellular Ca2+-mediated, Nox5-induced oxidative stress, and extracellular vesicle release in vascular smooth muscle …

P Petsophonsakul, M Burgmaier… - Cardiovascular …, 2022 - academic.oup.com
Aims Smokers are at increased risk of cardiovascular events. However, the exact
mechanisms through which smoking influences cardiovascular disease resulting in …

Targeting a silent disease: vascular calcification in chronic kidney disease

C Marreiros, C Viegas, D Simes - International Journal of Molecular …, 2022 - mdpi.com
Chronic kidney disease (CKD) patients have a higher risk of developing early
cardiovascular disease (CVD). Although vascular calcification (VC) is one of the strongest …

Medial arterial calcification: a significant and independent contributor of peripheral artery disease

C St. Hilaire - Arteriosclerosis, thrombosis, and vascular biology, 2022 - Am Heart Assoc
Over 200 million individuals worldwide are estimated to have peripheral artery disease
(PAD). Although the term peripheral can refer to any outer branch of the vasculature, the …

Highlighting the role of obesity and insulin resistance in type 1 diabetes and its associated cardiometabolic complications

G Karamanakos, A Kokkinos, M Dalamaga… - Current obesity reports, 2022 - Springer
Abstract Purpose of Review This narrative review appraises research data on the potentially
harmful effect of obesity and insulin resistance (IR) co-existence with type 1 diabetes …

Biomarkers of aging

Aging Biomarker Consortium, H Bao, J Cao… - Science China Life …, 2023 - Springer
Aging biomarkers are a combination of biological parameters to (i) assess age-related
changes,(ii) track the physiological aging process, and (iii) predict the transition into a …