Glioblastoma multiforme (GBM) has several distinctive characteristics linked to a poor early-
stage prognosis. The crucial obstacle in the treatment of GBM is the inability of chemo drugs …

Glioblastoma multiforme (GBM), a common malignant neurological tumor, has boundaries
indistinguishable from those of normal tissue, making complete surgical removal ineffective …

The objective of this work was to develop an implantable therapeutic hydrogel that will
ensure continuity in treatment between surgery and radiochemotherapy for patients with …

Brain drug delivery is severely hindered by the presence of the blood–brain barrier (BBB). Its
functionality relies on the interactions of the brain endothelial cells with additional cellular …

The management of brain tumors presents numerous challenges, despite the employment of
multimodal therapies including surgical intervention, radiotherapy, chemotherapy, and …

Drug combinations have been shown to be highly effective in many cancer therapies but the
ratios of the individual drugs must be adjusted carefully and formulated appropriately to …

Lipid nanocapsules (LNCs) are core-shell structures composed of an oily liquid triglyceride
core surrounded by a surfactant rigid membrane. LNCs are versatile carriers that can be …

Glioblastoma (GBM), an incurable brain tumor, necessitates surgery followed by
chemoradiation, but recurrences remain fatal. While regenerative responses post-tumor …