Covering: 2011 to 2022 The natural world is a prolific source of some of the most interesting,
rare, and complex molecules known, harnessing sophisticated biosynthetic machinery …

Covering: July 2015 to June 2017. Previous review: Nat. Prod. Rep., 2016, 33, 1318–1343
Recent progress on the isolation, identification, biological activity and synthetic studies of the …

The enantioselective synthesis of axially chiral biaryls by a copper-catalyzed Diels–
Alder/retro-Diels–Alder reaction of 2-pyrones with alkynes is reported herein. Using electron …

An inverse‐electron‐demand Diels–Alder (IEDDA) reaction could complement the
conventional normal‐electron‐demand Diels–Alder reaction in the synthesis of six …

A Cu-catalyzed diastereoselective [3+ 2] cycloaddition of 2-arylaziridines and cyclic silyl
dienol ethers was developed to efficiently construct fused-[5, n] carbocyclic pyrrolidines …

A novel strategy for the synthesis of cis‐decalins by an ytterbium‐catalyzed asymmetric
inverse‐electron‐demand Diels–Alder reaction of 2‐pyrones and silyl cyclohexadienol …

The Mannich reaction has been widely used to effectively construct C–N and C–C bonds in
organic synthesis. This review focuses on selected applications of the intramolecular …

Herein, we show that the combination of the Birch reduction of readily available anisole
derivatives and the catalytic asymmetric inverse‐electron‐demand Diels–Alder reaction of 2 …

The transition-metal-catalyzed allylation reaction is an efficient strategy for the construction
of new carbon–carbon bonds alongside allyl or homoallylic functionalization. Herein we …

Conspectus The field of total synthesis has reached a stage in which emphasis has been
increasingly focused on synthetic efficiency rather than merely achieving the synthesis of a …