Iron overload in patients undergoing hematopoietic stem cell transplantation

V Pullarkat - Advances in hematology, 2010 - Wiley Online Library
Recipients of hematopoietic stem cell transplantation (HSCT) frequently have iron overload
resulting from chronic transfusion therapy for anemia. In some cases, for example, in …

Metabolic instruction of the graft-versus-leukemia immunity

AC Burk, P Apostolova - Frontiers in immunology, 2024 - frontiersin.org
Allogeneic hematopoietic cell transplantation (allo-HCT) is frequently performed to cure
hematological malignancies, such as acute myeloid leukemia (AML), through the graft …

Changes in antioxidant defense system using different lipid emulsions in parenteral nutrition in children after hematopoietic stem cell transplantation

MA Baena-Gómez, MJ De La Torre Aguilar, MD Mesa… - Nutrients, 2015 - mdpi.com
Background: Traditionally, lipids used in parenteral nutrition (PN) are based on ω-6 fatty acid-
rich vegetable oils, such as soybean oil, with potential adverse effects involving oxidative …

Rapid cardiovascular aging following allogeneic hematopoietic cell transplantation for hematological malignancy

HT Dillon, S Foulkes, YA Horne-Okano… - Frontiers in …, 2022 - frontiersin.org
Introduction Allogeneic hematopoietic cell transplantation (allo-HCT) offers a potential cure
for high-risk hematological malignancy; however, long-term survivors experience increased …

hPMSCs prevent erythrocytes dysfunction caused by graft versus host disease via promoting GSH synthesis

Y Xiong, F Wang, H Mu, A Zhang, Y Zhao, K Han… - International …, 2024 - Elsevier
Background Oxidative stress is increased in allogeneic hematopoietic stem cell transplant
(allo-HSCT) recipients and leads to the development of graft versus host disease (GVHD) …

Kemoterapi, serbest radikaller ve oksidatif stres

S Sabuncuoğlu, H Özgüneş - … University Journal of the Faculty of …, 2011 - dergipark.org.tr
Antineoplastic agents induce oxidative stress in biological systems. During cancer
chemotherapy, oxidative stres is induced by numerous free radicals that can attack many …

Thiol/redox metabolomic profiling implicates GSH dysregulation in early experimental graft versus host disease (GVHD)

JH Suh, B Kanathezhath, S Shenvi, H Guo, A Zhou… - PloS one, 2014 - journals.plos.org
Graft-versus-host disease (GVHD) is a common complication of allogeneic bone marrow
transplantation (BMT). Upregulation of inflammatory cytokines precedes the clinical …

Evaluation of oxidative and antioxidative parameters in pediatric hematopoietic SCT patients

S Sabuncuoğlu, B Kuşkonmaz… - Bone marrow …, 2012 - nature.com
Conditioning regimens preceding hematopoietic SCT (HSCT) usually consist of high-dose
chemotherapy. Chemotherapy and radiation therapy are associated with increased …

Endogenous volatile organic compounds in acute myeloid leukemia: origins and potential clinical applications

D Dutta, NS Chong, SH Lim - Journal of Breath Research, 2018 - iopscience.iop.org
Not unlike many cancer types, acute myeloid leukemia (AML) exhibits many metabolic
changes and reprogramming, causing changes in lipid metabolism. Some of the distinct …

Protective effect of 2-hydroxy-4-methoxy benzoic acid on testosterone induced benign prostatic hyperplasia in Wister rats

MI Ali, HDP Kondreddi, B Veeresh - European journal of pharmacology, 2013 - Elsevier
Oxidative stress is one of the major causative factors for development of benign prostatic
hyperplasia (BPH). The aim of the present study is to evaluate the effect of 2-hydroxy-4 …