Safety of new biologics (vedolizumab and ustekinumab) and small molecules (tofacitinib) during pregnancy: a review

JP Gisbert, M Chaparro - Drugs, 2020 - Springer
Two new biological drugs (vedolizumab and ustekinumab) and one small molecule
(tofacitinib) have been recently approved for the treatment of inflammatory bowel disease …

European Crohn's and colitis guidelines on sexuality, fertility, pregnancy, and lactation

J Torres, M Chaparro, M Julsgaard… - Journal of Crohn's …, 2023 - academic.oup.com
2. Methods This document represents the third version of the European Consensus on
reproduction in IBD. The development of this Consensus included the formulation of …

Use of medications during pregnancy and breastfeeding for Crohn's disease and ulcerative colitis

R Laube, S Paramsothy, RW Leong - Expert Opinion on Drug …, 2021 - Taylor & Francis
Introduction: The peak age of diagnosis of inflammatory bowel disease (IBD) occurs during
childbearing years, therefore management of IBD during pregnancy is a frequent …

Immunosuppressives and biologics during pregnancy and lactation: A consensus report issued by the Austrian Societies of Gastroenterology and Hepatology and …

A Puchner, HP Gröchenig, J Sautner… - Wiener klinische …, 2019 - Springer
An increasing and early-onset use of immunosuppressives and biologics has become more
frequently seen among patients with inflammatory bowel diseases (IBD) and rheumatic …

New drugs for the treatment of IBD during conception, pregnancy, and lactation

D Pugliese, G Privitera, JP Gisbert… - Digestive and Liver …, 2024 - Elsevier
The management of inflammatory bowel disease requires continuous medical therapy to
achieve and maintain disease control. Thus, women can be exposed to different drugs …

[PDF][PDF] Tofacitinib concentrations in plasma and breastmilk of a lactating woman with ulcerative colitis

M Julsgaard, U Mahadevan… - Lancet …, 2023 - lirias.kuleuven.be
Exposure in utero and elimination of Adalimumab and Infliximab in neonates (the ERA study): a
prospective cohort study Page 1 1 Tofacitinib concentrations in plasma and breast milk of a …

Outcome of pregnancies in female patients with inflammatory bowel diseases treated with vedolizumab

A Moens, K van Hoeve, E Humblet… - Journal of Crohn's …, 2019 - academic.oup.com
Abstract Background and Aims Vedolizumab is an IgG1 anti-α4β7 integrin antibody
approved for the treatment of inflammatory bowel diseases [IBD], but without clear safety …

Vedolizumab clearance in neonates, susceptibility to infections and developmental milestones: a prospective multicentre population‐based cohort study

M Julsgaard, DC Baumgart… - Alimentary …, 2021 - Wiley Online Library
Background Little is known about the consequences of intrauterine exposure to, and the
post‐natal clearance of, vedolizumab. Aims To investigate the levels of vedolizumab in …

[HTML][HTML] Update on the management of inflammatory bowel disease during pregnancy and breastfeeding

S Restellini, L Biedermann, P Hruz, C Mottet, A Moens… - Digestion, 2020 - karger.com
Inflammatory bowel disease (IBD) affects patients during their peak reproductive years. This
raises important questions, in both patients and healthcare providers, regarding conception …

Transfer of monoclonal antibodies into breastmilk in neurologic and non-neurologic diseases

SC LaHue, A Anderson, KM Krysko… - Neurology …, 2020 - AAN Enterprises
Objective To review currently available data on the transfer of monoclonal antibodies (mAbs)
in the breastmilk of women receiving treatment for neurologic and non-neurologic diseases …