Hepatic fibrosis is a common pathological process involving persistent liver injury with
various etiologies and subsequent inflammatory responses that occur in chronic liver …

Hepatic macrophages play a central role in maintaining homeostasis in the liver, as well as
in the initiation and progression of liver diseases. Hepatic macrophages are mainly derived …

Liver fibrosis results from repeated and persistent liver damage. It can start with hepatocyte
injury and advance to inflammation, which recruits and activates additional liver immune …

Hepatic macrophage populations include different types of cells with plastic properties that
can differentiate into diverse phenotypes to modulate their properties in response to different …

Although several nanomedicines got clinical approval over the past two decades, the clinical
translation rate is relatively small so far. There are many post-surveillance withdrawals of …

Monocytes are circulating leukocytes of innate immunity derived from the bone marrow that
interact with endothelial cells under physiological or pathophysiological conditions to …

Cancer immunotherapy has been a favorable strategy for facilitating antitumor immunity.
However, immune tolerance and an ultimate immunosuppressive tumor microenvironment …

The liver is an important organ in the human body and performs many functions, such as
digestion, detoxification, metabolism, immune responses, and vitamin and mineral storage …

Summary Tumor-associated macrophages (TAMs), often adopting an immunosuppressive
M2-like phenotype, correlate with unfavorable cancer outcomes. Our investigation unveiled …

Liver diseases are the growing health problem with no clinically approved therapy available.
Activated hepatic stellate cells (HSCs) are the key driver cells responsible for extracellular …