Cellular and molecular evidence of multiple sclerosis diagnosis and treatment challenges
Multiple sclerosis (MS) is a chronic autoimmune disease that impacts the central nervous
system and can result in disability. Although the prevalence of MS has increased in India …
system and can result in disability. Although the prevalence of MS has increased in India …
Risk of new disease activity in patients with multiple sclerosis who continue or discontinue disease-modifying therapies (DISCOMS): a multicentre, randomised, single …
Background Multiple sclerosis typically has onset in young adults and new disease activity
diminishes with age. Most clinical trials of disease-modifying therapies for multiple sclerosis …
diminishes with age. Most clinical trials of disease-modifying therapies for multiple sclerosis …
Impact of aging on treatment considerations for multiple sclerosis patients
G Macaron, C Larochelle, N Arbour, M Galmard… - Frontiers in …, 2023 - frontiersin.org
With a rapidly aging global population and improvement of outcomes with newer multiple
sclerosis (MS)-specific disease-modifying therapies (DMTs), the epidemiology of MS has …
sclerosis (MS)-specific disease-modifying therapies (DMTs), the epidemiology of MS has …
Quantifying the risk of disease reactivation after interferon and glatiramer acetate discontinuation in multiple sclerosis: the VIAADISC score
G Bsteh, H Hegen, K Riedl, P Altmann… - European Journal of …, 2021 - Wiley Online Library
Background and purpose There is a lack of evidence guiding discontinuation of disease‐
modifying therapy (DMT) in relapsing multiple sclerosis (RMS). Thus, the objective of this …
modifying therapy (DMT) in relapsing multiple sclerosis (RMS). Thus, the objective of this …
Discontinuation of disease modifying therapies is associated with disability progression regardless of prior stable disease and age
D Jakimovski, KS Kavak, CB Vaughn… - Multiple Sclerosis and …, 2022 - Elsevier
Background Multiple sclerosis (MS) patients with stable disease course might view
continued treatment as unnecessary. However, guidelines regarding treatment …
continued treatment as unnecessary. However, guidelines regarding treatment …
Stopping disease-modifying therapy in relapsing and progressive multiple sclerosis
HP Hartung, SG Meuth, DM Miller… - Current Opinion in …, 2021 - journals.lww.com
Stopping disease-modifying therapy in relapsing and progress... : Current Opinion in Neurology
Stopping disease-modifying therapy in relapsing and progressive multiple sclerosis : Current …
Stopping disease-modifying therapy in relapsing and progressive multiple sclerosis : Current …
De-escalation and discontinuation of disease-modifying therapies in multiple sclerosis
RH Gross, J Corboy - Current Neurology and Neuroscience Reports, 2024 - Springer
Abstract Purpose of Review Long-term use of multiple sclerosis (MS) disease-modifying
therapies (DMTs) is standard practice to prevent accumulation of disability …
therapies (DMTs) is standard practice to prevent accumulation of disability …
Considering patient age when treating multiple sclerosis across the adult lifespan
D Jakimovski, SP Eckert, R Zivadinov… - Expert Review of …, 2021 - Taylor & Francis
Introduction: The successful development of anti-inflammatory disease-modifying treatments
(DMT) significantly improved disease outcomes and longevity of persons with multiple …
(DMT) significantly improved disease outcomes and longevity of persons with multiple …
[HTML][HTML] The future of progressive multiple sclerosis therapies
CW Hollen, MMP Soldán, JR Rinker, RI Spain - Federal …, 2020 - ncbi.nlm.nih.gov
Conclusions Developing effective disease modifying therapies that slow or stop the gradual
accumulation of neurologic disability in progressive MS represents a critical unmet need. As …
accumulation of neurologic disability in progressive MS represents a critical unmet need. As …
[HTML][HTML] A cross-sectional analysis of persistence to disease-modifying therapies in treatment naïve and experienced patients with relapsing multiple sclerosis at a …
MZ Kozlicki, B Markley, NB Shah, J DeClercq… - Multiple Sclerosis and …, 2022 - Elsevier
Background Patients with relapsing multiple sclerosis (RMS) are maintained on disease-
modifying therapy (DMT) to prevent disease progression. Reported persistence rates to …
modifying therapy (DMT) to prevent disease progression. Reported persistence rates to …