Hepatocellular carcinoma (HCC) is the most common primary liver malignancy and has a
poor prognosis. Epigenetic modification has been shown to be deregulated during HCC …

The primary reason for high mortality rates among cancer patients is metastasis, where
tumor cells migrate through the bloodstream from the original site to other parts of the body …

Despite the development of novel therapeutic approaches and improved clinical
management, survival from metastatic disease remains poor. Indeed, metastasis accounts …

Compared to advancements in single-cell proteomics, phosphoproteomics sensitivity has
lagged behind due to low abundance, complex sample preparation, and substantial sample …

PURPOSE Liquid biopsies can be used to investigate tumor-derived DNA, circulating in the
cell-free DNA (cfDNA) pool in blood. We aimed to develop a droplet digital polymerase …

As small non-coding RNAs, MicroRNAs (miRNAs) bind to the 3′ untranslated region (3′-
UTR) of mRNA targets to control gene transcription and translation. The gene of miR-330 …

Persistent inflammation can trigger altered epigenetic, inflammatory, and bioenergetic
states. Inflammatory bowel disease (IBD) is an idiopathic disease characterized by chronic …

IL-1 family members have multiple pleiotropic functions affecting various tissues and cells,
including the regulation of the immune response, hematopoietic homeostasis, bone …

Simple Summary Testicular germ cell tumors are the most common solid cancers in men
aged between 15–39 years. There is a need of non-invasive biomarkers for diagnosis and …

The Hippo signaling pathway was found coordinately modulates cell regeneration and
organ size. Its dysregulation contributes to uncontrolled cell proliferation and malignant …