Aptamers are short oligonucleotides isolated in vitro from randomized libraries that can bind
to specific molecules with high affinity, and offer a number of advantages relative to …

Nature achieves differentiation of specific and nonspecific binding in molecular interactions
through precise control of biomolecules in space and time. Artificial systems such as …

Wearable technologies for personalized monitoring require sensors that track biomarkers
often present at low levels. Cortisol—a key stress biomarker—is present in sweat at low …

Aptamers are short single-stranded DNA or RNA oligonucleotides isolated from randomized
libraries, presenting high affinity and specificity toward targets with similar to antibodies …

L‐lactate is a key metabolite indicative of physiological states, glycolysis pathways, and
various diseases such as sepsis, heart attack, lactate acidosis, and cancer. Detection of …

Tetracyclines are a group of important antibiotics with a common four-ring scaffold. While
most tetracyclines are currently used only in animals, their leaching into the environment …

Psychological stress is a major factor contributing to health discrepancies among
individuals. Sustained exposure to stress triggers signalling pathways in the brain, which …

We have developed a disposable point-of-care (POC) aptamer-based biosensor for the
detection of salivary cortisol. Nonstressful and noninvasive sampling of saliva compared to …

Aptamers are nucleic acid-based affinity reagents that have gained widespread attention as
biorecognition elements for the detection of targets such as ions, small molecules, and …

Aptamers are oligonucleotide receptors with great potential for sensing and therapeutic
applications. They are isolated from random libraries through an in vitro method termed …