The health effects of vitamin D supplementation: evidence from human studies

R Bouillon, D Manousaki, C Rosen… - Nature Reviews …, 2022 - nature.com
Vitamin D supplementation can prevent and cure nutritional rickets in infants and children.
Preclinical and observational data suggest that the vitamin D endocrine system has a wide …

[HTML][HTML] Vitamin D's effect on immune function

PJ Martens, C Gysemans, A Verstuyf, C Mathieu - Nutrients, 2020 - mdpi.com
Ever since its discovery by Windhaus, the importance of the active metabolite of vitamin D (1,
25-dihydroxyvitamin D 3; 1, 25-(OH) 2D 3) has been ever expanding. In this review, the …

An official American Thoracic Society/European Respiratory Society statement: update on limb muscle dysfunction in chronic obstructive pulmonary disease

F Maltais, M Decramer, R Casaburi… - American journal of …, 2014 - atsjournals.org
Background: Limb muscle dysfunction is prevalent in chronic obstructive pulmonary disease
(COPD) and it has important clinical implications, such as reduced exercise tolerance …

Role of diet in chronic obstructive pulmonary disease prevention and treatment

E Scoditti, M Massaro, S Garbarino, DM Toraldo - Nutrients, 2019 - mdpi.com
Chronic obstructive pulmonary disease is one of the leading causes of morbidity and
mortality worldwide and a growing healthcare problem. Identification of modifiable risk …

[HTML][HTML] Vitamin D and immune function

B Prietl, G Treiber, TR Pieber, K Amrein - Nutrients, 2013 - mdpi.com
Vitamin D metabolizing enzymes and vitamin D receptors are present in many cell types
including various immune cells such as antigen-presenting-cells, T cells, B cells and …

Comorbidities of COPD

A Cavaillès, G Brinchault-Rabin… - European …, 2013 - Eur Respiratory Soc
By 2020, chronic obstructive pulmonary disease (COPD) will be the third cause of mortality.
Extrapulmonary comorbidities influence the prognosis of patients with COPD. Tobacco …

Links between inflammatory bowel disease and chronic obstructive pulmonary disease

AL Raftery, E Tsantikos, NL Harris… - Frontiers in …, 2020 - frontiersin.org
Inflammatory bowel disease (IBD) and chronic obstructive pulmonary disease (COPD) are
chronic inflammatory diseases of the gastrointestinal and respiratory tracts, respectively …

Common genetic determinants of vitamin D insufficiency: a genome-wide association study

TJ Wang, F Zhang, JB Richards, B Kestenbaum… - The Lancet, 2010 - thelancet.com
Background Vitamin D is crucial for maintenance of musculoskeletal health, and might also
have a role in extraskeletal tissues. Determinants of circulating 25-hydroxyvitamin D …

Managing comorbidities in COPD

G Hillas, F Perlikos, I Tsiligianni… - International journal of …, 2015 - Taylor & Francis
Chronic obstructive pulmonary disease (COPD) is a leading cause of morbidity and mortality
worldwide. Age and smoking are common risk factors for COPD and other illnesses, often …

Cellular metabolism and macrophage functional polarization

L Zhu, Q Zhao, T Yang, W Ding… - International reviews of …, 2015 - Taylor & Francis
Macrophages are a functionally heterogeneous cell population that is mainly shaped by a
variety of microenvironmental stimuli. Interferon γ (IFN-γ), interleukin-1β (IL-1β), and …