Dysfunctional signaling in midbrain reward circuits perpetuates diseases characterized by
compulsive overconsumption of rewarding substances such as substance abuse, binge …

The growth hormone secretagogue receptor (GHSR) is a G-protein-coupled receptor
(GPCR) highly expressed in the brain, and also in some peripheral tissues. GHSR activity is …

Ghrelin is a stomach-derived hormone that regulates rewarding behaviors and
reinforcement by acting on the ventral tegmental area (VTA). The VTA is a complex midbrain …

Current literature indicates that the orexigenic peptide ghrelin increases appetitive
motivation via signaling in the mesolimbic reward system. Another gastric peptide, glucagon …

Most psychiatric disorders are characterized by deficits in the ability to interact socially with
others. Ghrelin, a hormone normally associated with the regulation of glucose utilization and …

The present study examined the ability of ghrelin administration into either the ventral
tegmental area (VTA) or nucleus accumbens (NAc) to potentiate cocaine-induced …

Growth hormone secretagogue receptor (GHSR), the receptor for ghrelin, is expressed in
key brain nuclei that regulate food intake. The dopamine (DA) pathways have long been …

Growth hormone secretagogue receptor type 1A (GHSR-1A) is a functional receptor of
orexigenic peptide ghrelin and is highly expressed in mesolimbic dopaminergic systems that …

Ghrelin, a hormone secreted by the stomach, binds to the growth hormone secretagogue
receptor (GHSR) in various brain regions to produce a number of behavioral effects that …

Gene expression profiling across various brain areas at the single-cell resolution enables
the identification of molecular markers of neuronal subpopulations and comprehensive …