Mechanisms of spinal cord stimulation for the treatment of pain: still in the dark after 50 years

MP Jensen, RM Brownstone - European journal of pain, 2019 - Wiley Online Library
Abstract Background and Objective Despite the value of spinal cord stimulation (SCS) in
treating some patients with focal neuropathic pain, technological advances in stimulator …

New trends in neuromodulation for the management of neuropathic pain

KM Alo, J Holsheimer - Neurosurgery, 2002 - journals.lww.com
Abstract SINCE ITS FIRST application in 1967, the methodology and technology of spinal
cord stimulation for the management of chronic, intractable pain have evolved continuously …

A prospective, randomised, double-blind, placebo-controlled study to examine the effectiveness of burst spinal cord stimulation patterns for the treatment of failed back …

S Schu, PJ Slotty, G Bara, M von Knop, D Edgar… - … : Technology at the …, 2014 - Elsevier
Objectives: Spinal cord stimulation (SCS) for the treatment of chronic pain is a well-
established therapy. However, the requirement that paresthesia be continually felt by the …

Stepping-like movements in humans with complete spinal cord injury induced by epidural stimulation of the lumbar cord: electromyographic study of compound …

K Minassian, B Jilge, F Rattay, MM Pinter, H Binder… - Spinal cord, 2004 - nature.com
Study design: It has been previously demonstrated that sustained nonpatterned electric
stimulation of the posterior lumbar spinal cord from the epidural space can induce stepping …

A multicenter, prospective trial to assess the safety and performance of the spinal modulation dorsal root ganglion neurostimulator system in the treatment of chronic …

L Liem, M Russo, FJPM Huygen, JP Van Buyten… - … : Technology at the …, 2013 - Elsevier
Objectives This multicenter prospective trial was conducted to evaluate the clinical
performance of a new neurostimulation system designed to treat chronic pain through the …

Stimulation of the human lumbar spinal cord with implanted and surface electrodes: a computer simulation study

J Ladenbauer, K Minassian… - … on Neural Systems …, 2010 - ieeexplore.ieee.org
Human lumbar spinal cord networks controlling stepping and standing can be activated
through posterior root stimulation using implanted electrodes. A new stimulation method …

Human lumbar cord circuitries can be activated by extrinsic tonic input to generate locomotor-like activity

K Minassian, I Persy, F Rattay, MM Pinter, H Kern… - Human movement …, 2007 - Elsevier
We have demonstrated that non-patterned electrical stimulation of the lumbar cord can
induce stepping-like activity in the lower limbs of complete spinal cord injured individuals …

Computational analysis of kilohertz frequency spinal cord stimulation for chronic pain management

SF Lempka, CC McIntyre, KL Kilgore… - Anesthesiology, 2015 - pubs.asahq.org
Background: Kilohertz frequency spinal cord stimulation (KHFSCS) is an emerging therapy
for treating refractory neuropathic pain. Although KHFSCS has the potential to improve the …

Epidural spinal-cord stimulation facilitates recovery of functional walking following incomplete spinal-cord injury

MR Carhart, J He, R Herman… - … on neural systems …, 2004 - ieeexplore.ieee.org
We investigated a novel treatment paradigm for developing functional ambulation in
wheelchair-dependent individuals with chronic, incomplete spinal-cord injury. By …

[PDF][PDF] Sensor-driven position-adaptive spinal cord stimulation for chronic pain

DM Schultz, LR Webster, P Kosek, U Dar… - Pain …, 2012 - painphysicianjournal.com
Background: Variation in the intensity of neurostimulation due to body position is a practical
problem for many patients implanted with spinal cord stimulation (SCS) systems because …