The molecular interactions underlying regulation of the immune response take place in a
nanoscale gap between T cells and antigen-presenting cells, termed the immunological …

The protein-protein interaction underlying l&and recogmtion by CD2 must ensure sprcifuty
while allowing for wry weak binding. The CD5Rbmdmg site on human CD2 has nuw brrn …

This standard-setting textbook has defined the field of immunology since 1984, and is now in
its Seventh Edition continuing to deliver the detailed, authoritative, and timely coverage …

We report that diffuse large B cell lymphoma (DLBCL) commonly fails to express cell-surface
molecules necessary for the recognition of tumor cells by immune-effector cells. In 29% of …

Rolling of leukocytes on vascular endotheliai cells, an early event in inflammation, can be
reproduced in vitro on artificial lipid bilayers containing purified CD62, a seiectln also named …

Cytokine-activated human endothelial cells express vascular cell adhesion molecule-
l(VCAM-l), which binds lymphocytes. We now identify the in&grin VLA-4 as a receptor for …

ISG15 is a ubiquitin-like protein that functions in innate immunity both as an intracellular
protein modifier and as an extracellular signaling molecule that stimulates IFN-γ secretion …

Lymphocyte function-associated antigen 1 (LFA-1) is a leukocyte cell surface giycopmtein
that promotes intelrceiiuiar adhesion in immunoiogicai and inflammatory reactions. it is an …

Effective interaction between T cells and their targets requires that recognition of specific
antigen be coordinated with increased cell-cell adhesion. We show that antigen-receptor …

While the leukocyte integrin lymphocyte function-associated antigen (LFA)-1 has been
demonstrated to bind intercellular adhesion molecule (ICAM)-1, results with the related Mac …