[HTML][HTML] Pyroptosis and its role in the modulation of cancer progression and antitumor immunity

S Qi, Q Wang, J Zhang, Q Liu, C Li - International journal of molecular …, 2022 - mdpi.com
Pyroptosis is a type of programmed cell death (PCD) accompanied by an inflammatory
reaction and the rupture of a membrane. Pyroptosis is divided into a canonical pathway …

[HTML][HTML] Pyroptosis and its role in cervical cancer

K Li, J Qiu, J Pan, JP Pan - Cancers, 2022 - mdpi.com
Simple Summary Pyroptosis is a kind of programmed cell death, which is characterized by
pore formation in the plasma membrane and the release of large amounts of inflammatory …

Pancancer transcriptomic profiling identifies key PANoptosis markers as therapeutic targets for oncology

R Mall, RR Bynigeri, R Karki, RKS Malireddi… - NAR …, 2022 - academic.oup.com
Resistance to programmed cell death (PCD) is a hallmark of cancer. While some PCD
components are prognostic in cancer, the roles of many molecules can be masked by …

[HTML][HTML] Molecular investigation of candidate genes for pyroptosis-induced inflammation in diabetic retinopathy

N Wang, L Ding, D Liu, Q Zhang, G Zheng… - Frontiers in …, 2022 - frontiersin.org
Background Diabetic retinopathy is a diabetic microvascular complication. Pyroptosis, as a
way of inflammatory death, plays an important role in the occurrence and development of …

[HTML][HTML] The p-STAT3/ANXA2 axis promotes caspase-1-mediated hepatocyte pyroptosis in non-alcoholic steatohepatitis

Y Feng, W Li, Z Wang, R Zhang, Y Li, L Zang… - Journal of Translational …, 2022 - Springer
Background To explore the roles of Annexin A2 (ANXA2) on hepatocyte pyroptosis and
hepatic fibrosis in nonalcoholic steatohepatitis (NASH) and underlying molecular …

Non-apoptotic cell death programs in cervical cancer with an emphasis on ferroptosis

M Samare-Najaf, A Samareh, A Savardashtaki… - Critical Reviews in …, 2023 - Elsevier
Background Cervical cancer, a pernicious gynecological malignancy, causes the mortality of
hundreds of thousands of females worldwide. Despite a considerable decline in mortality …

[HTML][HTML] Bulk and single-cell transcriptome analyses of islet tissue unravel gene signatures associated with pyroptosis and immune infiltration in type 2 diabetes

Y Song, C He, Y Jiang, M Yang, Z Xu, L Yuan… - Frontiers in …, 2023 - frontiersin.org
Introduction Type 2 diabetes (T2D) is a common chronic heterogeneous metabolic disorder.
However, the roles of pyroptosis and infiltrating immune cells in islet dysfunction of patients …

Pyroptosis-Related Gene Signature Predicts Prognosis and Response to Immunotherapy and Medication in Pediatric and Young Adult Osteosarcoma Patients

C Guo, X Yang, L Li - Journal of Inflammation Research, 2024 - Taylor & Francis
Purpose Pyroptosis, a new form of inflammatory programmed cell death, has recently gained
attention. However, the impact of the expression levels of pyroptosis-related genes (PRGs) …

增强子调控癌症发生发展的机制研究

漆思晗, 王棨临, 张俊有, 刘倩, 李春燕 - 遗传, 2022 - chinagene.cn
增强子是一段具有转录调控功能的DNA 序列, 主要通过顺式调控方式发挥作用.
由于增强子及其调控基因在位置和距离上的不确定性, 大大增加了研究增强子作用机制的复杂性 …