Acetazolamide: Old drug, new evidence?

AA Shukralla, E Dolan, N Delanty - Epilepsia Open, 2022 - Wiley Online Library
Acetazolamide is an old drug used as an antiepileptic agent, amongst other indications. The
drug is seldom used, primarily due to perceived poor efficacy and adverse events …

Role of mitochondrial mechanism in chemotherapy-induced peripheral neuropathy

M Waseem, P Kaushik, H Tabassum… - Current drug …, 2018 - ingentaconnect.com
Background: Even though chemotherapeutic regimens show considerable importance, it
may cause progressive, continuing and sometimes irreversible peripheral neuropathy …

Research progress on the structure and biological diversities of 2-phenylindole derivatives in recent 20 years

P Wu, J Zhao, X Shen, X Liang, C He, L Yin, F Xu… - Bioorganic …, 2023 - Elsevier
The privileged structure binds to multiple receptors with high affinity, which is helpful to the
development of new bioactive compounds. Indole is classified as a privileged structure …

Oncotic cell death in stroke

KY Loh, Z Wang, P Liao - Reviews of Physiology, Biochemistry and …, 2019 - Springer
Oncotic cell death or oncosis represents a major mechanism of cell death in ischaemic
stroke, occurring in many central nervous system (CNS) cell types including neurons, glia …

Acid-sensing ion channel 1a is involved in N-methyl D-aspartate receptor-dependent long-term depression in the hippocampus

D Mango, R Nisticò - Frontiers in pharmacology, 2019 - frontiersin.org
Acid-sensing ion channels (ASICs), members of the degenerin/epithelial Na+ channel
superfamily, are largely expressed in the mammalian nervous system. ASIC1a is highly …

Acid-sensing ion channel 1a is required for mGlu receptor dependent long-term depression in the hippocampus

D Mango, E Braksator, G Battaglia, S Marcelli… - Pharmacological …, 2017 - Elsevier
Acid-sensing ion channels (ASICs), members of the degenerin/epithelial Na+ channel
superfamily, are widely distributed in the mammalian nervous system. ASIC1a is highly …

Factors and molecular mechanisms influencing the protein synthesis, degradation and membrane trafficking of ASIC1a

Y Xu, F Chen - Frontiers in Cell and Developmental Biology, 2020 - frontiersin.org
Acid-sensing ion channels (ASICs) are members of the degenerin/epithelial sodium channel
superfamily. They are extracellular pH sensors that are activated by protons. Among all …

[HTML][HTML] 三聚体配体门控离子通道胞内区域的功能研究进展

鲁燕, 林义雨, 汪津 - Journal of Zhejiang University (Medical …, 2024 - ncbi.nlm.nih.gov
配体门控离子通道是一大类重要的膜蛋白。 嘌呤能配体门控离子通道( P2X)
受体和酸敏感离子通道( ASIC) 是三聚体配体门控离子通道的代表成员。 P2X …

ASIC1a Involves the Acid-Mediated Activation of Pancreatic Stellate Cells Associated With Autophagy Induction

W Tao, W Qianqian, PAN Guixia… - Physiological …, 2022 - pmc.ncbi.nlm.nih.gov
The acidic tumor microenvironment (TME) of pancreatic cancer affects the physiological
function of pancreatic stellate cells (PSCs), which in turn promotes cancer progression. Acid …

Influence of acid-sensing ion channel blocker on behavioral responses in a zebrafish model of acute visceral pain

IA Adedara, FV Costa, E Biasuz, J Canzian… - Behavioural Brain …, 2022 - Elsevier
Acid-sensing ion channels (ASICs) play significant roles in numerous neurological and
pathological conditions, including pain. Although acid-induced nociception has been …