Hepatic fibrosis is a dynamic process characterized by the net accumulation of extracellular
matrix resulting from chronic liver injury of any aetiology, including viral infection, alcoholic …

Progressive liver fibrosis, induced by chronic viral and metabolic disorders, leads to more
than one million deaths annually via development of cirrhosis, although no antifibrotic …

The molecular pathology of multi-organ injuries in COVID-19 patients remains unclear,
preventing effective therapeutics development. Here, we report a proteomic analysis of 144 …

Liver fibrosis is a reversible wound-healing process aimed at maintaining organ integrity,
and presents as the critical pre-stage of liver cirrhosis, which will eventually progress to …

Nonalcoholic steatohepatitis (NASH) is emerging as a leading cause of chronic liver
disease. However, therapeutic options are limited by incomplete understanding of the …

Inflammation is an adaptive response in pursuit of homeostasis reestablishment triggered by
harmful conditions or stimuli, such as an infection or tissue damage. Liver diseases cause …

Although fibrosis is a final pathological feature of many chronic diseases, few interventions
are available that specifically target the pathogenesis of fibrosis. Natural products are …

Ethanol misuse is frequently associated with a multitude of profound medical conditions,
contributing to health-, individual-and social-related damage. A particularly dangerous threat …

Abstract Background Triclosan [5-chloro-2-(2, 4-dichlorophenoxy) phenol, TCS], a common
antimicrobial additive in many personal care and health care products, is frequently detected …

Tyro3, AXL, and MerTK (TAM) receptors are activated in macrophages in response to tissue
injury and as such have been proposed as therapeutic targets to promote inflammation …