Response of contrast agents to ultrasound

V Sboros - Advanced drug delivery reviews, 2008 - Elsevier
Microbubbles are used as ultrasonic contrast agents that enhance the ultrasound signals of
the vascular bed. The recent development of site-targeted microbubbles opened up the …

Characterizing how size distribution and concentration affect echogenicity of ultrasound contrast agents

B Koo, Y Liu, M Abboud, B Qin, Y Wu, S Choi, D Kozak… - Ultrasonics, 2023 - Elsevier
We investigated the effects of UCA gas bubble size distribution and concentration on the
generated ultrasound echogenicity signal. Gas bubble size characterization using Coulter …

Estimating the shell parameters of SonoVue® microbubbles using light scattering

J Tu, J Guan, Y Qiu, TJ Matula - The Journal of the Acoustical Society …, 2009 - pubs.aip.org
Experiments were performed to measure the dynamical response of individual SonoVue®
microbubbles subjected to pulsed ultrasound. Three commonly used bubble dynamic …

Investigation of the relationship of nonlinear backscattered ultrasound intensity with microbubble concentration at low MI

M Lampaskis, M Averkiou - Ultrasound in medicine & biology, 2010 - Elsevier
The aim of this study was to measure the relationship of image intensity with contrast agent
concentration. In vitro experiments were performed with a flow phantom and a sulphur …

Using optical scattering to measure properties of ultrasound contrast agent shells

T Matula, J Guan - US Patent 7,804,595, 2010 - Google Patents
A system and method for determining bubble shell properties using optical scattering. One
or more ultrasound contrast agent (UCA) bubbles is placed in an imaging volume and …

Destruction thresholds of echogenic liposomes with clinical diagnostic ultrasound

DAB Smith, TM Porter, J Martinez, S Huang… - Ultrasound in medicine …, 2007 - Elsevier
Echogenic liposomes (ELIP) are submicron-sized phospholipid vesicles that contain both
gas and fluid. With antibody conjugation and drug incorporation, these liposomes can be …

Using light scattering to measure the response of individual ultrasound contrast microbubbles subjected to pulsed ultrasound in vitro

J Guan, TJ Matula - The Journal of the Acoustical Society of America, 2004 - pubs.aip.org
Light scattering was used to measure the radial pulsations of individual ultrasound contrast
microbubbles subjected to pulsed ultrasound. Highly diluted Optison® or Sonazoid® …

Nanomechanics of biocompatible hollow thin-shell polymer microspheres

E Glynos, V Koutsos, WN McDicken, CM Moran… - Langmuir, 2009 - ACS Publications
The nanomechanical properties of biocompatible thin-shell hollow polymer microspheres
with approximately constant ratio of shell thickness to microsphere diameter were measured …

Hydrogel based tissue mimicking phantom for in‐vitro ultrasound contrast agents studies

C Demitri, A Sannino, F Conversano… - … Research Part B …, 2008 - Wiley Online Library
Ultrasound medical imaging (UMI) is the most widely used image analysis technique, and
often requires advanced in‐vitro set up to perform morphological and functional …

Absolute measurement of ultrasonic backscatter from single microbubbles

V Sboros, SD Pye, CA MacDonald, J Gomatam… - Ultrasound in medicine …, 2005 - Elsevier
Good quality acoustical experiments are needed to measure microbubble behavior. An
absolute calibration of the transmitted ultrasound field is possible using a calibrated …