Dexamethasone (DEX) has been widely used to treat a variety of diseases, including
autoimmune diseases, allergies, ocular disorders, cancer, and, more recently, COVID-19 …

Sufficient ocular bioavailability is often considered a challenge by the researchers, due to
the complex structure of the eye and its protective physiological mechanisms. In addition, the …

Nanotherapeutics based on biocompatible lipid matrices allow for enhanced solubility of
poorly soluble compounds in the treatment of ophthalmic diseases, overcoming the …

This work aimed to optimize a celecoxib (CXB)-loaded solid lipid nanoparticles (SLN) colon
delivery system for the enhancement of anticancer activity. An ultrasonic melt-emulsification …

Recent years have witnessed a boom in ocular nanomedicine research with a number of
lipid-based nanocarriers such as liposomes, niosomes, cubosomes, nanoemulsions, solid …

Bacterial conjunctivitis (BC) entails inflammation of the ocular mucous membrane. Early
effective treatment of BC can prevent the spread of the infection to the intraocular tissues …

Clozapine is commonly used to treat schizophrenia but it is having issues of low oral
bioavailability (< 27%), degradation in GI environment and high hepatic first-pass …

The opposing effect of the blood–brain barrier against the delivery of most drugs warrants
the need for an efficient brain targeted drug delivery system for the successful management …

The present research work was designed to prepare Azithromycin (AM)-loaded nano lipid
carriers (NLs) for ocular delivery. NLs were prepared by the emulsification–homogenization …

Corticosteroids, although highly effective for the treatment of both anterior and posterior
ocular segment inflammation, still nowadays struggle for effective drug delivery due to their …