Enhancing permeation of drug molecules across the skin via delivery in nanocarriers: novel strategies for effective transdermal applications

YQ Yu, X Yang, XF Wu, YB Fan - Frontiers in bioengineering and …, 2021 - frontiersin.org
The transdermal route of administration provides numerous advantages over conventional
routes ie, oral or injectable for the treatment of different diseases and cosmetics applications …

Lipid nanoparticles as carriers for bioactive delivery

N Dhiman, R Awasthi, B Sharma, H Kharkwal… - Frontiers in …, 2021 - frontiersin.org
Nanotechnology has made a great impact on the pharmaceutical, biotechnology, food, and
cosmetics industries. More than 40% of the approved drugs are lipophilic and have poor …

Potential of nanoparticles as permeation enhancers and targeted delivery options for skin: Advantages and disadvantages

P Ghasemiyeh… - Drug design, development …, 2020 - Taylor & Francis
The topical route of administration has many advantages for the treatment of various skin
disorders as well as cosmeceutical purposes. This route bypasses hepatic first-pass effect …

[HTML][HTML] Nanostructured lipid carriers for site-specific drug delivery

A Khosa, S Reddi, RN Saha - Biomedicine & Pharmacotherapy, 2018 - Elsevier
Nanostructured lipid carriers (NLC), comprises of a blend of solid and liquid lipids which
results in a partially crystallized lipid system and imparts many advantages over solid lipid …

Synthesis and potential applications of lipid nanoparticles in medicine

E Musielak, A Feliczak-Guzik, I Nowak - Materials, 2022 - mdpi.com
Currently, carriers of active ingredients in the form of particles of a size measured in
nanometers are the focus of interest of research centers worldwide. So far, submicrometer …

Lipid nanoparticles: Different preparation techniques, characterization, hurdles, and strategies for the production of solid lipid nanoparticles and nanostructured lipid …

P Ganesan, D Narayanasamy - Sustainable Chemistry and Pharmacy, 2017 - Elsevier
The bioavailability of an orally administered drug primarily depends on its solubility in the
GIT and its permeability across cell membranes. Also, a drug in solution form is preferred for …

Nanostructured lipid carriers: Promising drug delivery systems for future clinics

A Beloqui, MÁ Solinís, A Rodríguez-Gascón… - … , biology and medicine, 2016 - Elsevier
During the past decade, the number of studies describing nanostructured lipid carriers
(NLCs)-based formulations has been dramatically increased. The raise in NLC exploitation …

Silk fibroin nanoparticle as a novel drug delivery system

F Mottaghitalab, M Farokhi, MA Shokrgozar… - Journal of Controlled …, 2015 - Elsevier
Abstract Design and synthesis of efficient drug delivery systems are of vital importance for
medicine and healthcare. Nanocarrier-based drug delivery systems, in particular …

Optimization of nanostructured lipid carriers: Understanding the types, designs, and parameters in the process of formulations

B Subramaniam, ZH Siddik, NH Nagoor - Journal of nanoparticle research, 2020 - Springer
Lipid-based nanoparticles for drug delivery have been employed in the development of
nanomedicine for various applications. One such versatile nanoparticle type is …

Lipid nanoparticles (SLN, NLC) in cosmetic and pharmaceutical dermal products

J Pardeike, A Hommoss, RH Müller - International journal of pharmaceutics, 2009 - Elsevier
Solid lipid nanoparticles (SLN) are distinguishable from nanostructured lipid carriers (NLC)
by the composition of the solid particle matrix. Both are an alternative carrier system to …