The introduction of the E Factor in 1992 focussed attention on the problem of waste
generation, defined as everything but the desired product, in chemicals manufacture and …

Electrochemistry has recently gained increased attention as a versatile strategy for
achieving challenging transformations at the forefront of synthetic organic chemistry …

Biocatalysis has found numerous applications in various fields as an alternative to chemical
catalysis. The use of enzymes in organic synthesis, especially to make chiral compounds for …

Direct substitution of readily available alcohols is recognized as a key research area in
green chemical synthesis. Starting from simple racemic secondary alcohols, the …

Dipolar aprotic and ethereal solvents comprise just over 40% of all organic solvents utilized
in synthetic organic, medicinal, and process chemistry. Unfortunately, many of the common …

The development of new green methodologies and their broader adoption for promoting
sustainable development in chemistry laboratories and industry play a significant role in …

A growing number of organopnictogen redox catalytic methods have emerged—especially
within the past 10 years—that leverage the plentiful reversible two-electron redox chemistry …

As a new type of porous crystalline material, hydrogen-bonded organic frameworks (HOFs)
assemble through intermolecular hydrogen bonds of organic building blocks. The unique …

Developing greener synthesis processes is an inescapable necessity to transform the
industrial landscape, mainly in the pharmaceutical sector, into a long-term, sustainable …

This review describes the practical aspects involved in the implementation of large-scale
amidations in process chemistry. Coupling reagent, base, additive, and solvent selections …