Bovine tuberculosis is a serious infectious disease affecting a wide range of domesticated
and wild animals, representing a worldwide economic and public health burden. The …

Background Next-generation sequencing (NGS) technologies are being used to predict
antimicrobial resistance. The field is evolving rapidly and transitioning out of the research …

The emergence and spread of resistant tuberculosis (TB) pose a threat to public health, so it
is necessary to diagnose the drug-resistant forms in a clinically short time frame and closely …

Abstract Background Drug resistant Mycobacterium tuberculosis prevention and care is a
major challenge in Ethiopia. The World health organization has designated Ethiopia as one …

Tuberculosis, caused by Mycobacterium tuberculosis, is a high-burden disease in Pakistan,
with multi-drug (MDR) and extensive-drug (XDR) resistance, complicating infection control …

Tuberculosis (TB), caused by Mycobacterium tuberculosis, is endemic in Pakistan.
Resistance to both firstline rifampicin and isoniazid drugs (multidrug-resistant TB; MDR-TB) …

Drug resistance in Mycobacterium tuberculosis, the causative agent of tuberculosis disease,
arises from genetic mutations in genes coding for drug-targets or drug-converting enzymes …

Resistance mutations in Mycobacterium tuberculosis (Mtb) catalase peroxidase protein
(KatG), an essential enzyme in isoniazid (INH) activation, reduce the sensitivity of Mtb to first …

Background Leveraging well-established DNA-level drug resistance mechanisms, whole-
genome sequencing (WGS) has emerged as a valuable methodology for predicting drug …

Peru has the highest burden of multidrug-resistant tuberculosis in the Americas region.
Since 1999, the annual number of extensively drug-resistant tuberculosis (XDR-TB) …