Hidradenitis suppurativa: an update on epidemiology, phenotypes, diagnosis, pathogenesis, comorbidities and quality of life

TV Nguyen, G Damiani, LAV Orenstein… - Journal of the …, 2021 - Wiley Online Library
Hidradenitis suppurativa (HS) is a chronic inflammatory skin disease that severely impairs
patients' quality of life. It is characterized by recurrent painful nodules, abscesses and …

Prevalence of hidradenitis suppurativa: a systematic review and meta-regression analysis

A Jfri, D Nassim, E O'Brien, W Gulliver… - JAMA …, 2021 - jamanetwork.com
Importance Hidradenitis suppurativa/acne inversa (HS) is a chronic inflammatory skin
disease characterized by occlusion of hair follicles as a primary pathogenic factor. There are …

Secukinumab in moderate-to-severe hidradenitis suppurativa (SUNSHINE and SUNRISE): week 16 and week 52 results of two identical, multicentre, randomised …

AB Kimball, GBE Jemec, A Alavi, Z Reguiai, AB Gottlieb… - The Lancet, 2023 - thelancet.com
Background Few therapeutic options are available for patients with moderate-to-severe
hidradenitis suppurativa. We aimed to assess the efficacy of secukinumab in patients with …

[HTML][HTML] Comorbidity screening in hidradenitis suppurativa: evidence-based recommendations from the US and Canadian Hidradenitis Suppurativa Foundations

A Garg, N Malviya, A Strunk, S Wright, A Alavi… - Journal of the American …, 2022 - Elsevier
Background Hidradenitis suppurativa (HS) is associated with comorbidities that contribute to
poor health, impaired life quality, and mortality risk. Objective To provide evidence-based …

What causes hidradenitis suppurativa?—15 years after

CC Zouboulis, F Benhadou, AS Byrd… - Experimental …, 2020 - Wiley Online Library
The 14 authors of the first review article on hidradenitis suppurativa (HS) pathogenesis
published 2008 in EXPERIMENTAL DERMATOLOGY cumulating from the 1st International …

Janus kinase 1 inhibitor INCB054707 for patients with moderate‐to‐severe hidradenitis suppurativa: results from two phase II studies

A Alavi, I Hamzavi, K Brown, LL Santos… - British Journal of …, 2022 - academic.oup.com
Background Janus kinase (JAK)‐mediated cytokine signalling contributes to local and
systemic inflammation in hidradenitis suppurativa (HS). Objectives To describe the safety …

Biologics for hidradenitis suppurativa: evolution of the treatment paradigm

CA Maronese, C Moltrasio, G Genovese… - Expert Review of …, 2024 - Taylor & Francis
Introduction Hidradenitis suppurativa (HS) is an autoinflammatory skin disease with a high
unmet need for effective medical management. Clinically, it is characterized by inflammatory …

Pain management in hidradenitis suppurativa and a proposed treatment algorithm

KT Savage, V Singh, ZS Patel, CA Yannuzzi… - Journal of the American …, 2021 - Elsevier
Pain contributes substantially to reduced quality of life in individuals living with hidradenitis
suppurativa (HS). Although improved understanding of HS pathogenesis and treatment has …

Quality of life in hidradenitis suppurativa: an update

PV Chernyshov, AY Finlay, L Tomas-Aragones… - International journal of …, 2021 - mdpi.com
Knowledge on hidradenitis suppurativa/acne inversa (HS) is rapidly increasing. HS has a
profound impact on patients and their family life. Several factors, such as comorbidities …

Review of comorbidities of hidradenitis suppurativa: implications for daily clinical practice

T Tzellos, CC Zouboulis - Dermatology and therapy, 2020 - Springer
Hidradenitis suppurativa (HS) is a chronic, recurrent skin inflammatory disease associated
with a variety of comorbidities, like reduced quality of life, metabolic syndrome, sexual …