Since their discovery in the late 1960s, 1-azabicyclo [1.1. 0] butanes have demonstrated to
be interesting precursors of azetidines, because of the peculiar reactivity of the C3–N bond …

Recent advances in the field of ring‐expansion chemistry, involving 1‐azoniabicyclo [n. 1.0]
alkane scaffolds (bicyclic aziridinium ions) as key transient intermediates, have made it …

The facile synthesis of functionalized azetidines has been an ongoing challenge. Here, we
report a general method to directly alkylate 1-azabicyclo [1.1. 0] butane (ABB) with …

A broad overview is given concerning the synthesis of 3-haloazetidines and 3-
sulfonyloxyazetidines. The importance of these compounds is highlighted by numerous …

The three‐component reactions of 1‐azabicyclo [1.1. 0] butanes 1, dicyanofumarates (E)‐5,
and MeOH or morpholine yielded azetidine enamines 8 and 9 with the cis‐orientation of the …

1-Azabicyclo [1.1. 0] butane (ABB, 1) reacted with 3-acyl-1, 3-thiazolidine-2-thiones (7,
11a―m) in the presence of a catalytic amount of Mg (OTf) 2 to give the corresponding 2-(1 …

Despite the favourable properties that azetidine rings can engender drug-compounds with,
methods for the modular synthesis of azetidine-based structures are significantly …

The reaction of 3-phenyl-1-azabicyclo [1.1. 0] butane (1c) with 2, 3-dicyanofumarates ((E)-5)
in dichloromethane at room temperature yields mixtures of cis-and trans-2, 3-dicyano-4 …

The diastereoselective synthesis of cis-1, 4-disubstituted morpholines has been
accomplished in good to excellent yields via Bi (OTf) 3 catalyzed ring-closing O-allylation …

The reaction of fluoral hydrate with carbohydrazides in methanol in the presence of
molecular sieves (4 Å) gave the desired N-acylated fluoral hydrazones (3a–f) in fair yields …