The interaction between insulin and exercise is an example of balancing and modifying the
effects of two opposing metabolic regulatory forces under varying conditions. While insulin is …

BACKGROUND Polycystic ovary syndrome (PCOS) is a common endocrine disorder,
affecting 8–12% of women. Lifestyle modification, including increased physical activity, is the …

Glucocorticoids are steroid hormones produced by the adrenal cortex and are essential for
the maintenance of various metabolic and homeostatic functions. Their function is regulated …

Today, we know that a primary metabolic action of insulin is to facilitate the postprandial
disposition of glucose via its actions on three key target tissues: suppression of glucose …

Exercise training improves insulin sensitivity in subjects with and without type 2 diabetes.
However, the mechanism by which this occurs is unclear. The present study was undertaken …

The purpose of this study was to investigate the mechanisms explaining improved insulin-
stimulated glucose uptake after exercise training in human skeletal muscle. Eight healthy …

Despite evidence of the benefits of physical activity, most individuals with type 2 diabetes do
not meet physical activity recommendations. The purpose of this study was to test the …

Le syndrome de la mort par sédentarité (SeDS) provoque de nombreuses maladies
chroniques et des millions de décès prématurés chaque année. De ce fait, il est devenu un …

OBJECTIVE Insulin resistance in diet-induced obesity (DIO) is associated with a chronic
systemic low-grade inflammation, and Toll–like receptor 4 (TLR4) plays an important role in …

IRS1 and IRS2 are the most important representatives of the IRS protein family and critical
nodes in insulin/IGF1-signaling. Although they are quite similar in their structural and …