Deep learning-enabled realistic virtual histology with ultraviolet photoacoustic remote sensing microscopy
The goal of oncologic surgeries is complete tumor resection, yet positive margins are
frequently found postoperatively using gold standard H&E-stained histology methods …
frequently found postoperatively using gold standard H&E-stained histology methods …
Metabolic light absorption, scattering, and emission (MetaLASE) microscopy
Optical imaging of metabolism can provide key information about health and disease
progression in cells and tissues; however, current methods have lacked gold-standard …
progression in cells and tissues; however, current methods have lacked gold-standard …
Label-free complete absorption microscopy using second generation photoacoustic remote sensing
BR Ecclestone, K Bell, S Sparkes, D Dinakaran… - Scientific Reports, 2022 - nature.com
In the past decades, absorption modalities have emerged as powerful tools for label-free
functional and structural imaging of cells and tissues. Many biomolecules present unique …
functional and structural imaging of cells and tissues. Many biomolecules present unique …
Harnessing the power of optical microscopy for visualization and analysis of histopathological images
N Wang, C Zhang, X Wei, T Yan, W Zhou… - Biomedical Optics …, 2023 - opg.optica.org
Histopathology is the foundation and gold standard for identifying diseases, and precise
quantification of histopathological images can provide the pathologist with objective clues to …
quantification of histopathological images can provide the pathologist with objective clues to …
Rapid ultraviolet photoacoustic remote sensing microscopy using voice-coil stage scanning
There is an unmet need for fast virtual histology technologies that exhibit histological realism
and can scan large sections of fresh tissue within intraoperative time-frames. Ultraviolet …
and can scan large sections of fresh tissue within intraoperative time-frames. Ultraviolet …
Three-dimensional virtual histology in unprocessed resected tissues with photoacoustic remote sensing (PARS) microscopy and optical coherence tomography (OCT)
Histological images are critical in the diagnosis and treatment of cancers. Unfortunately,
current methods for capturing these microscopy images require resource intensive tissue …
current methods for capturing these microscopy images require resource intensive tissue …
Virtual histopathology with ultraviolet scattering and photoacoustic remote sensing microscopy
Realistic label-free virtual histopathology has been a long sought-after goal not yet achieved
with current methods. Here, we introduce high-resolution hematoxylin and eosin (H&E)-like …
with current methods. Here, we introduce high-resolution hematoxylin and eosin (H&E)-like …
Miniature non-contact photoacoustic probe based on fiber-optic photoacoustic remote sensing microscopy
Photoacoustic (PA) remote sensing (PARS) microscopy, featured by non-contact operation,
has shown great potential for PA microscopy (PAM) imaging applications. However, current …
has shown great potential for PA microscopy (PAM) imaging applications. However, current …
Simultaneous deep ultraviolet transmission and scattering microscopy for virtual histology
In recent years, the emergence of a variety of novel optical microscopy techniques has
enabled the generation of virtual optical stains of unlabeled tissue specimens, which have …
enabled the generation of virtual optical stains of unlabeled tissue specimens, which have …
Label-free virtual Hematoxylin and Eosin (H&E) staining using second generation Photoacoustic Remote Sensing (PARS)
BR Ecclestone, K Bell, S Sparkes, D Dinakaran… - arXiv preprint arXiv …, 2021 - arxiv.org
In the past decades, absorption modalities have emerged as powerful tools for label-free
functional and structural imaging of cells and tissues. Many biomolecules present unique …
functional and structural imaging of cells and tissues. Many biomolecules present unique …