A large body of evidence indicates the existence of functionally polarized CD4+ T‐cell
responses based on their profile of cytokine secretion. Type 1 T helper (Th1) cells produce …

Recent evidence has been accumulated to suggest that allergen-reactive type 2 helper T
cells (Th2) play a triggering role in the activation and/or recruitment of IgE antibody …

WHEN activated, T helper cells differentiate into one of two subsets, Th1 and Th2,
characterized by distinct profiles of cytokine production. Th1 cells activate pro-inflammatory …

EVERY cell contains many families of protein kinases, and may express several structurally
related yet genetically distinct kinases of each family. The activity of the serine/threonine …

Cells expressing the chemoattractant receptor‐homologous molecule expressed on Th2
cells (CRTH2) and the chemokine C receptor (CCR) 4 were consistently detected in the …

The identification of distinct T helper lymphocyte subsets (Th1/2) with polarised cytokine
production has opened up new fields in immunobiology. Of the several alternative methods …

In both mice and humans, functionally distinct helper T (Th)-cell subsets, known as Th1 and
Th2 cells, are characterized by the patterns of cytokines they produce. These two polarized …

The capacity of endothelial cells (EC) to produce IL-15 and the capacity of IL-15 to influence
transendothelial migration of T cells was examined. Human umbilical vein endothelial cells …

The sequences of thousands of proteins are accessible in scientific databases and their
number is steadily growing. Protein sequences from a great number of pathogens are thus …

The preferential association of some chemokine receptors with human Th1 or Th2 cells has
recently been reported. In this study, the expression of CCR3, CCR5, CXCR3, and CXCR4 …