Alzheimer's disease (AD) is the most prevalent form of dementia, with complex
pathophysiology that is not fully understood. While β‐amyloid plaque and neurofibrillary …

It is well known that neurodegenerative diseases' development and progression are
accelerated due to oxidative stress and inflammation, which result in impairment of …

Bacopa monnieri (Brahmi) is a well-known perennial, creeping herb of the Indian Ayurveda
system; it contains numerous bioactive phytoconstituents implicated in the therapeutic …

Intranasal administration is a promising route for brain drug delivery. However, it can be
difficult to formulate drugs that have low water solubility into high strength intranasal …

The perineuronal net (PNN) is a highly latticed extracellular matrix in the central nervous
system, which is composed of hyaluronic acid, proteoglycan, hyaluronan and proteoglycan …

Aging reduces homeostasis and contributes to increasing the risk of brain diseases and
death. Some of the principal characteristics are chronic and low-grade inflammation, a …

Alzheimer's disease (AD) is the most prevalent form of dementia, characterized by the
presence of plaques of amyloid beta and Tau proteins. There is currently no permanent cure …

Background: Alzheimer's disease (AD) is the most common form of dementia worldwide,
with approximately 6 million cases reported in America in 2020. The clinical signs of AD …

Tau is an intrinsically disordered neuronal protein in the central nervous system. Aggregated
Tau is the main component of neurofibrillary tangles observed in Alzheimer's disease. In …

Alzheimer's disease (AD), a neurodegenerative disorder, is a major health concern in the
increasingly aged population worldwide. Currently, no clinically effective drug can halt the …