Turning'sweet'on immunity: galectin–glycan interactions in immune tolerance and inflammation
GA Rabinovich, MA Toscano - Nature Reviews Immunology, 2009 - nature.com
The function of deciphering the biological information encoded by the glycome, which is the
entire repertoire of complex sugar structures expressed by cells and tissues, is assigned in …
entire repertoire of complex sugar structures expressed by cells and tissues, is assigned in …
Galectins: structure, function and therapeutic potential
RY Yang, GA Rabinovich, FT Liu - Expert reviews in molecular …, 2008 - cambridge.org
Galectins are a family of animal lectins that bind β-galactosides. Outside the cell, galectins
bind to cell-surface and extracellular matrix glycans and thereby affect a variety of cellular …
bind to cell-surface and extracellular matrix glycans and thereby affect a variety of cellular …
Regulation of transforming growth factor-β1–driven lung fibrosis by galectin-3
AC MacKinnon, MA Gibbons, SL Farnworth… - American journal of …, 2012 - atsjournals.org
Rationale: Idiopathic pulmonary fibrosis (IPF) is a chronic dysregulated response to alveolar
epithelial injury with differentiation of epithelial cells and fibroblasts into matrix-secreting …
epithelial injury with differentiation of epithelial cells and fibroblasts into matrix-secreting …
Galectin-1: a small protein with major functions
I Camby, M Le Mercier, F Lefranc, R Kiss - Glycobiology, 2006 - academic.oup.com
Galectins are a family of carbohydrate-binding proteins with an affinity for β-galactosides.
Galectin-1 (Gal-1) is differentially expressed by various normal and pathological tissues and …
Galectin-1 (Gal-1) is differentially expressed by various normal and pathological tissues and …
Galectins: regulators of acute and chronic inflammation
FT Liu, GA Rabinovich - Annals of the New York Academy of …, 2010 - Wiley Online Library
Galectins, β‐galactoside‐binding animal lectins, are differentially expressed by various
immune cells as well as a wide range of other cell types. Extracellularly, galectins are able to …
immune cells as well as a wide range of other cell types. Extracellularly, galectins are able to …
Galectins and immune responses—just how do they do those things they do?
S Thiemann, LG Baum - Annual review of immunology, 2016 - annualreviews.org
Galectins are a family of mammalian carbohydrate-binding proteins expressed by many cell
types. Galectins can function intracellularly and can also be secreted to bind to cell surface …
types. Galectins can function intracellularly and can also be secreted to bind to cell surface …
Animal lectins: a historical introduction and overview
DC Kilpatrick - Biochimica et biophysica acta (BBA)-General subjects, 2002 - Elsevier
Some proteins we now regard as animal lectins were discovered before plant lectins, though
many were not recognised as carbohydrate-binding proteins for many years after first being …
many were not recognised as carbohydrate-binding proteins for many years after first being …
Galectins and their ligands: amplifiers, silencers or tuners of the inflammatory response?
GA Rabinovich, LG Baum, N Tinari, R Paganelli… - Trends in …, 2002 - cell.com
Recent evidence has implicated galectins and their ligands as master regulators of immune
cell homeostasis. Whereas some members of this family, such as galectin-3, behave as …
cell homeostasis. Whereas some members of this family, such as galectin-3, behave as …
The role of galectins as modulators of metabolism and inflammation
MF Brinchmann, DM Patel… - Mediators of …, 2018 - Wiley Online Library
Galectins are β‐galcotosid‐binding lectins. The function of galectins varies with their tissue‐
specific and subcellular location, and their binding to carbohydrates makes them key players …
specific and subcellular location, and their binding to carbohydrates makes them key players …