Deep-lipidotyping by mass spectrometry: recent technical advances and applications
In-depth structural characterization of lipids is an essential component of lipidomics. There
has been a rapid expansion of mass spectrometry methods that are capable of resolving …
has been a rapid expansion of mass spectrometry methods that are capable of resolving …
Ion mobility mass spectrometry for the separation and characterization of small molecules
Small molecules with molecular weights less than 1500 Da represented by natural
metabolites such as amino acids, nucleotides, carbohydrates, lipids, flavonoids, alkaloids …
metabolites such as amino acids, nucleotides, carbohydrates, lipids, flavonoids, alkaloids …
High-confidence structural identification of metabolites relying on tandem mass spectrometry through isomeric identification: A tutorial
Y Song, Q Song, W Liu, J Li, P Tu - TrAC Trends in Analytical Chemistry, 2023 - Elsevier
MS/MS currently serves as the workhorse for metabolomics. Structural identification is
extremely important to correlate statistical variables to biochemical functions and …
extremely important to correlate statistical variables to biochemical functions and …
Different ion mobility‐mass spectrometry coupling techniques to promote metabolomics
A Delvaux, E Rathahao‐Paris… - Mass Spectrometry …, 2022 - Wiley Online Library
Metabolomics has become increasingly popular in recent years for many applications
ranging from clinical diagnosis, human health to biotechnological questioning. Despite …
ranging from clinical diagnosis, human health to biotechnological questioning. Despite …
Perspective on emerging mass spectrometry technologies for comprehensive lipid structural elucidation
JR Bonney, BM Prentice - Analytical chemistry, 2021 - ACS Publications
Lipids and metabolites are of interest in many clinical and research settings because it is the
metabolome that is increasingly recognized as a more dynamic and sensitive molecular …
metabolome that is increasingly recognized as a more dynamic and sensitive molecular …
High-resolution demultiplexing (HRdm) ion mobility spectrometry–mass spectrometry for aspartic and isoaspartic acid determination and screening
KE Butler, JN Dodds, T Flick, IDG Campuzano… - Analytical …, 2022 - ACS Publications
Isomeric peptide analyses are an analytical challenge of great importance to therapeutic
monoclonal antibody and other biotherapeutic product development workflows. Aspartic …
monoclonal antibody and other biotherapeutic product development workflows. Aspartic …
Chiral derivatization-enabled discrimination and on-tissue detection of proteinogenic amino acids by ion mobility mass spectrometry
C Xie, Y Chen, X Wang, Y Song, Y Shen, X Diao… - Chemical …, 2022 - pubs.rsc.org
The importance of chiral amino acids (AAs) in living organisms has been widely recognized
since the discovery of endogenous D-AAs as potential biomarkers in several metabolic …
since the discovery of endogenous D-AAs as potential biomarkers in several metabolic …
Quantification of biocatalytic transformations by single microbial cells enabled by tailored integration of droplet microfluidics and mass spectrometry
K Wink, M van Der Loh, N Hartner… - Angewandte Chemie …, 2022 - Wiley Online Library
Improving the performance of chemical transformations catalysed by microbial biocatalysts
requires a deep understanding of cellular processes. While the cellular heterogeneity of …
requires a deep understanding of cellular processes. While the cellular heterogeneity of …
Algorithms for de-novo sequencing of peptides by tandem mass spectrometry: A review
CCA Ng, Y Zhou, ZP Yao - Analytica Chimica Acta, 2023 - Elsevier
Peptide sequencing is of great significance to fundamental and applied research in the
fields such as chemical, biological, medicinal and pharmaceutical sciences. With the rapid …
fields such as chemical, biological, medicinal and pharmaceutical sciences. With the rapid …
Advanced mass spectrometric and spectroscopic methods coupled with machine learning for in vitro diagnosis
In vitro diagnosis (IVD) is one vital component of medical tests that detects biological
samples of tissues or bio‐fluids. Recently, mass spectrometry and spectroscopy have been …
samples of tissues or bio‐fluids. Recently, mass spectrometry and spectroscopy have been …