Obstructive sleep apnoea heterogeneity and cardiovascular disease

S Redline, A Azarbarzin, Y Peker - Nature Reviews Cardiology, 2023 - nature.com
Obstructive sleep apnoea (OSA), characterized by recurrent periods of upper airway
obstruction and intermittent hypoxaemia, is prevalent in patients with cardiovascular disease …

Bidirectional relationships of comorbidity with obstructive sleep apnoea

M Gleeson, WT McNicholas - European respiratory review, 2022 - Eur Respiratory Soc
Obstructive sleep apnoea (OSA) is frequently associated with comorbidities that include
metabolic, cardiovascular, renal, pulmonary and neuropsychiatric. There is considerable …

Obstructive sleep apnoea and cardiovascular consequences: pathophysiological mechanisms

C Arnaud, T Bochaton, JL Pépin, E Belaidi - Archives of cardiovascular …, 2020 - Elsevier
Obstructive sleep apnoea syndrome is a growing health concern, affecting nearly one billion
people worldwide; it is an independent cardiovascular risk factor, associated with incident …

International consensus statement on obstructive sleep apnea

JL Chang, AN Goldberg, JA Alt… - International forum of …, 2023 - Wiley Online Library
Background Evaluation and interpretation of the literature on obstructive sleep apnea (OSA)
allows for consolidation and determination of the key factors important for clinical …

The relationship between inflammation and neurocognitive dysfunction in obstructive sleep apnea syndrome

X Liu, Y Ma, R Ouyang, Z Zeng, Z Zhan, H Lu… - Journal of …, 2020 - Springer
Obstructive sleep apnea syndrome (OSAS), a state of sleep disorder, is characterized by
repetitive apnea, chronic hypoxia, oxygen desaturation, and hypercapnia. Previous studies …

[HTML][HTML] Pathobiological mechanisms underlying metabolic syndrome (MetS) in chronic obstructive pulmonary disease (COPD): clinical significance and therapeutic …

SMH Chan, S Selemidis, S Bozinovski… - Pharmacology & …, 2019 - Elsevier
Chronic obstructive pulmonary disease (COPD) is a major incurable global health burden
and is currently the 4th largest cause of death in the world. Importantly, much of the disease …

Models of intermittent hypoxia and obstructive sleep apnea: molecular pathways and their contribution to cancer

I Hunyor, KM Cook - American Journal of Physiology …, 2018 - journals.physiology.org
Obstructive sleep apnea (OSA) is common and linked to a variety of poor health outcomes. A
key modulator of this disease is nocturnal intermittent hypoxia. There is striking …

Technical feasibility and physiological relevance of hypoxic cell culture models

J Pavlacky, J Polak - Frontiers in endocrinology, 2020 - frontiersin.org
Hypoxia is characterized as insufficient oxygen delivery to tissues and cells in the body and
is prevalent in many human physiology processes and diseases. Thus, it is an attractive …

Obesity and obstructive sleep apnea

MR Bonsignore - From Obesity to Diabetes, 2021 - Springer
Obstructive sleep apnea (OSA) is characterized by upper airway collapse during sleep.
Chronic intermittent hypoxia, sleep fragmentation, and inflammatory activation are the main …

Adipose tissue as a key player in obstructive sleep apnoea

S Ryan, C Arnaud, SF Fitzpatrick… - European …, 2019 - Eur Respiratory Soc
Obstructive sleep apnoea (OSA) is a major health concern worldwide and adversely affects
multiple organs and systems. OSA is associated with obesity in> 60% of cases and is …