[HTML][HTML] AI-assisted prediction of differential response to antidepressant classes using electronic health records
Antidepressant selection is largely a trial-and-error process. We used electronic health
record (EHR) data and artificial intelligence (AI) to predict response to four antidepressants …
record (EHR) data and artificial intelligence (AI) to predict response to four antidepressants …
[HTML][HTML] Evaluating cognitive disturbances as treatment target and predictor of antidepressant action in major depressive disorder: a NeuroPharm study
Cognitive disturbances in major depressive disorder (MDD) constitute a critical treatment
target and hold promise as an early predictor of antidepressant treatment response; yet their …
target and hold promise as an early predictor of antidepressant treatment response; yet their …
[HTML][HTML] Systemic DNA and RNA damage from oxidation after serotonergic treatment of unipolar depression
A Jorgensen, K Köhler-Forsberg, T Henriksen… - Translational …, 2022 - nature.com
Previous studies have indicated that antidepressants that inhibit the serotonin transporter
reduces oxidative stress. DNA and RNA damage from oxidation is involved in aging and a …
reduces oxidative stress. DNA and RNA damage from oxidation is involved in aging and a …
Serotonin 4 receptor brain binding in major depressive disorder and association with memory dysfunction
Importance The cerebral serotonin 4 (5-HT 4) receptor is a promising novel target for
treatment of major depressive disorder (MDD), and pharmacological stimulation of the 5-HT …
treatment of major depressive disorder (MDD), and pharmacological stimulation of the 5-HT …
PET‐MRI Applications and Future Prospects in Psychiatry
This article reviews the synergistic application of positron emission tomography‐magnetic
resonance imaging (PET‐MRI) in neuroscience with relevance for psychiatry, particularly …
resonance imaging (PET‐MRI) in neuroscience with relevance for psychiatry, particularly …
[HTML][HTML] Sexual health and serotonin 4 receptor brain binding in unmedicated patients with depression—a NeuroPharm study
Sexual dysfunction is prominent in Major Depressive Disorder (MDD) and affects women
with depression more than men. Patients with MDD relative to healthy controls have lower …
with depression more than men. Patients with MDD relative to healthy controls have lower …
[HTML][HTML] Management of post-stroke depression (PSD) by electroencephalography for effective rehabilitation
B Yang, Y Huang, Z Li, X Hu - Engineered Regeneration, 2023 - Elsevier
Post-stroke depression (PSD) has negative impacts on the daily life of stroke survivors and
delays their neurological recovery. However, traditional post-stroke rehabilitation mainly …
delays their neurological recovery. However, traditional post-stroke rehabilitation mainly …
Hyperconnectivity between the posterior cingulate and middle frontal and temporal gyrus in depression: Based on functional connectivity meta-analyses
Disrupted whole-brain resting-state functional connectivity (RSFC) of the posterior cingulate
(PCC) has been highlighted to associate with cognitive and affective dysfunction in major …
(PCC) has been highlighted to associate with cognitive and affective dysfunction in major …
[HTML][HTML] Concurrent anxiety in patients with major depression and cerebral serotonin 4 receptor binding. A NeuroPharm-1 study
Concurrent anxiety is frequent in major depressive disorder and a shared
pathophysiological mechanism between anxiety and other depressive symptoms is …
pathophysiological mechanism between anxiety and other depressive symptoms is …
Emotional faces processing in major depressive disorder and prediction of antidepressant treatment response: a NeuroPharm study
Background: Major depressive disorder (MDD) is a prevalent neuropsychiatric illness for
which it is important to resolve underlying brain mechanisms. Current treatments are often …
which it is important to resolve underlying brain mechanisms. Current treatments are often …