Global epidemiology of dementia: Alzheimer's and vascular types

L Rizzi, I Rosset, M Roriz-Cruz - BioMed research international, 2014 - Wiley Online Library
The prevalence of dementia varies substantially worldwide. This is partially attributed to the
lack of methodological uniformity among studies, including diagnostic criteria and different …

Alzheimer's disease and vascular dementia in developing countries: prevalence, management, and risk factors

RN Kalaria, GE Maestre, R Arizaga… - The Lancet …, 2008 - thelancet.com
Despite mortality due to communicable diseases, poverty, and human conflicts, dementia
incidence is destined to increase in the developing world in tandem with the ageing …

Alzheimer's disease and metabolic syndrome: A link from oxidative stress and inflammation to neurodegeneration

E Rojas‐Gutierrez, G Muñoz‐Arenas, S Treviño… - Synapse, 2017 - Wiley Online Library
Alzheimer's disease (AD) is the most common cause of dementia and one of the most
important causes of morbidity and mortality among the aging population. AD diagnosis is …

Metabolic-cognitive syndrome: a cross-talk between metabolic syndrome and Alzheimer's disease

V Frisardi, V Solfrizzi, D Seripa, C Capurso… - Ageing research …, 2010 - Elsevier
A growing body of epidemiological evidence suggested that metabolic syndrome (MetS) and
Mets components (impaired glucose tolerance, abdominal or central obesity, hypertension …

Executive function, memory, and gait speed decline in well-functioning older adults

NL Watson, C Rosano, RM Boudreau… - … Series A: Biomedical …, 2010 - academic.oup.com
Background. In community-dwelling older adults, global cognitive function predicts
longitudinal gait speed decline. Few prospective studies have evaluated whether specific …

Metabolic syndrome and cognitive decline in the elderly: a systematic review

N Assuncao, FK Sudo, C Drummond, FG de Felice… - PloS one, 2018 - journals.plos.org
Background Metabolic Syndrome (MetS) refers to a cluster of metabolic disturbances which
is associated with increased risk for vascular and degenerative conditions in general …

Visceral adipose NLRP3 impairs cognition in obesity via IL-1R1 on CX3CR1+ cells

DH Guo, M Yamamoto, CM Hernandez… - The Journal of …, 2020 - Am Soc Clin Investig
Induction of the inflammasome protein cryopyrin (NLRP3) in visceral adipose tissue (VAT)
promotes release of the proinflammatory cytokine IL-1β in obesity. Although this mechanism …

[HTML][HTML] (Pre) diabetes, brain aging, and cognition

JS Roriz-Filho, TM Sá-Roriz, I Rosset… - Biochimica et biophysica …, 2009 - Elsevier
Cognitive dysfunction and dementia have recently been proven to be common (and
underrecognized) complications of diabetes mellitus (DM). In fact, several studies have …

Metabolic syndrome and cognitive impairment: current epidemiology and possible underlying mechanisms

F Panza, V Frisardi, C Capurso… - Journal of …, 2010 - content.iospress.com
A possible role of vascular and lifestyle-related factors was recently proposed for age-
related changes of cognitive function, predementia syndromes, and cognitive decline of …

Recruiting adaptive cellular stress responses for successful brain ageing

AM Stranahan, MP Mattson - Nature Reviews Neuroscience, 2012 - nature.com
Successful ageing is determined in part by genetic background, but also by experiential
factors associated with lifestyle and culture. Dietary, behavioural and pharmacological …