[HTML][HTML] Getting around the cell: physical transport in the intracellular world

SS Mogre, AI Brown, EF Koslover - Physical Biology, 2020 - iopscience.iop.org
Eukaryotic cells face the challenging task of transporting a variety of particles through the
complex intracellular milieu in order to deliver, distribute, and mix the many components that …

[HTML][HTML] RNA granules hitchhike on lysosomes for long-distance transport, using annexin A11 as a molecular tether

YC Liao, MS Fernandopulle, G Wang, H Choi, L Hao… - Cell, 2019 - cell.com
Long-distance RNA transport enables local protein synthesis at metabolically-active sites
distant from the nucleus. This process ensures an appropriate spatial organization of …

The vertebrate Balbiani body, germ plasm, and oocyte polarity

A Jamieson-Lucy, MC Mullins - Current topics in developmental biology, 2019 - Elsevier
The fate of future generations depends on a high-quality germ line. For a female to
successfully produce offspring, her oocytes must be successfully specified and their contents …

L-bodies are RNA–protein condensates driving RNA localization in Xenopus oocytes

CR Neil, SP Jeschonek, SE Cabral… - Molecular biology of …, 2021 - Am Soc Cell Biol
Ribonucleoprotein (RNP) granules are membraneless compartments within cells, formed by
phase separation, that function as regulatory hubs for diverse biological processes …

Dynamic visualization of transcription and RNA subcellular localization in zebrafish

PD Campbell, JA Chao, RH Singer… - Development, 2015 - journals.biologists.com
Live imaging of transcription and RNA dynamics has been successful in cultured cells and
tissues of vertebrates but is challenging to accomplish in vivo. The zebrafish offers important …

Molecular motors: directing traffic during RNA localization

JA Gagnon, KL Mowry - Critical reviews in biochemistry and …, 2011 - Taylor & Francis
RNA localization, the enrichment of RNA in a specific subcellular region, is a mechanism for
the establishment and maintenance of cellular polarity in a variety of systems. Ultimately, this …

RNA localization and transport

B Suter - Biochimica et Biophysica Acta (BBA)-Gene Regulatory …, 2018 - Elsevier
RNA localization serves numerous purposes from controlling development and
differentiation to supporting the physiological activities of cells and organisms. After a brief …

An RNA‐binding atypical tropomyosin recruits kinesin‐1 dynamically to oskar mRNPs

I Gáspár, V Sysoev, A Komissarov, A Ephrussi - The EMBO Journal, 2017 - embopress.org
Localization and local translation of oskar mRNA at the posterior pole of the Drosophila
oocyte directs abdominal patterning and germline formation in the embryo. The process …

Biological scaling problems and solutions in amphibians

DL Levy, R Heald - Cold Spring Harbor perspectives in …, 2016 - cshperspectives.cshlp.org
Size is a primary feature of biological systems that varies at many levels, from the organism
to its constituent cells and subcellular structures. Amphibians populate some of the extremes …

Invasion by exogenous RNA: cellular defense strategies and implications for RNA inference

D Tang, Y Liu, C Wang, L Li, SA Al-Farraj… - Marine Life Science & …, 2023 - Springer
Exogenous RNA poses a continuous threat to genome stability and integrity across various
organisms. Accumulating evidence reveals complex mechanisms underlying the cellular …