Neuronal cell-type classification: challenges, opportunities and the path forward
Neurons have diverse molecular, morphological, connectional and functional properties. We
believe that the only realistic way to manage this complexity—and thereby pave the way for …
believe that the only realistic way to manage this complexity—and thereby pave the way for …
Disentangling neural cell diversity using single-cell transcriptomics
Cellular specialization is particularly prominent in mammalian nervous systems, which are
composed of millions to billions of neurons that appear in thousands of different'flavors' and …
composed of millions to billions of neurons that appear in thousands of different'flavors' and …
[PDF][PDF] The Allen mouse brain common coordinate framework: a 3D reference atlas
Recent large-scale collaborations are generating major surveys of cell types and
connections in the mouse brain, collecting large amounts of data across modalities, spatial …
connections in the mouse brain, collecting large amounts of data across modalities, spatial …
[PDF][PDF] Integrated morphoelectric and transcriptomic classification of cortical GABAergic cells
NW Gouwens, SA Sorensen, F Baftizadeh, A Budzillo… - Cell, 2020 - cell.com
Neurons are frequently classified into distinct types on the basis of structural, physiological,
or genetic attributes. To better constrain the definition of neuronal cell types, we …
or genetic attributes. To better constrain the definition of neuronal cell types, we …
Hierarchical organization of cortical and thalamic connectivity
The mammalian cortex is a laminar structure containing many areas and cell types that are
densely interconnected in complex ways, and for which generalizable principles of …
densely interconnected in complex ways, and for which generalizable principles of …
[HTML][HTML] Shared and distinct transcriptomic cell types across neocortical areas
The neocortex contains a multitude of cell types that are segregated into layers and
functionally distinct areas. To investigate the diversity of cell types across the mouse …
functionally distinct areas. To investigate the diversity of cell types across the mouse …
Mouse retinal cell atlas: molecular identification of over sixty amacrine cell types
Amacrine cells (ACs) are a diverse class of interneurons that modulate input from
photoreceptors to retinal ganglion cells (RGCs), rendering each RGC type selectively …
photoreceptors to retinal ganglion cells (RGCs), rendering each RGC type selectively …
[PDF][PDF] A suite of transgenic driver and reporter mouse lines with enhanced brain-cell-type targeting and functionality
Modern genetic approaches are powerful in providing access to diverse cell types in the
brain and facilitating the study of their function. Here, we report a large set of driver and …
brain and facilitating the study of their function. Here, we report a large set of driver and …
Genetic dissection of the glutamatergic neuron system in cerebral cortex
Diverse types of glutamatergic pyramidal neurons mediate the myriad processing streams
and output channels of the cerebral cortex,, yet all derive from neural progenitors of the …
and output channels of the cerebral cortex,, yet all derive from neural progenitors of the …
[HTML][HTML] Cellular anatomy of the mouse primary motor cortex
An essential step toward understanding brain function is to establish a structural framework
with cellular resolution on which multi-scale datasets spanning molecules, cells, circuits and …
with cellular resolution on which multi-scale datasets spanning molecules, cells, circuits and …