Metabolomics for investigating physiological and pathophysiological processes
DS Wishart - Physiological reviews, 2019 - journals.physiology.org
Metabolomics uses advanced analytical chemistry techniques to enable the high-throughput
characterization of metabolites from cells, organs, tissues, or biofluids. The rapid growth in …
characterization of metabolites from cells, organs, tissues, or biofluids. The rapid growth in …
To metabolomics and beyond: a technological portfolio to investigate cancer metabolism
F Danzi, R Pacchiana, A Mafficini, MT Scupoli… - … and Targeted Therapy, 2023 - nature.com
Tumour cells have exquisite flexibility in reprogramming their metabolism in order to support
tumour initiation, progression, metastasis and resistance to therapies. These reprogrammed …
tumour initiation, progression, metastasis and resistance to therapies. These reprogrammed …
Lung cancer scRNA-seq and lipidomics reveal aberrant lipid metabolism for early-stage diagnosis
Lung cancer is the leading cause of cancer mortality, and early detection is key to improving
survival. However, there are no reliable blood-based tests currently available for early-stage …
survival. However, there are no reliable blood-based tests currently available for early-stage …
Metabolomics Workbench: An international repository for metabolomics data and metadata, metabolite standards, protocols, tutorials and training, and analysis tools
Abstract The Metabolomics Workbench, available at www. metabolomicsworkbench. org, is
a public repository for metabolomics metadata and experimental data spanning various …
a public repository for metabolomics metadata and experimental data spanning various …
Atlas of circadian metabolism reveals system-wide coordination and communication between clocks
Metabolic diseases are often characterized by circadian misalignment in different tissues,
yet how altered coordination and communication among tissue clocks relate to specific …
yet how altered coordination and communication among tissue clocks relate to specific …
Quality assurance procedures for mass spectrometry untargeted metabolomics. a review
Untargeted metabolomics, as a global approach, has already proven its great potential and
capabilities for the investigation of health and disease, as well as the wide applicability for …
capabilities for the investigation of health and disease, as well as the wide applicability for …
Single-cell metabolomics: analytical and biological perspectives
R Zenobi - Science, 2013 - science.org
Background In recent years, there has been a surge in the development and application of
single-cell genomics, transcriptomics, proteomics, and metabolomics. The metabolome is …
single-cell genomics, transcriptomics, proteomics, and metabolomics. The metabolome is …
MetaboLights—an open-access general-purpose repository for metabolomics studies and associated meta-data
Abstract MetaboLights (http://www. ebi. ac. uk/metabolights) is the first general-purpose,
open-access repository for metabolomics studies, their raw experimental data and …
open-access repository for metabolomics studies, their raw experimental data and …
Systems biology primer: the basic methods and approaches
I Tavassoly, J Goldfarb, R Iyengar - Essays in biochemistry, 2018 - portlandpress.com
Systems biology is an integrative discipline connecting the molecular components within a
single biological scale and also among different scales (eg cells, tissues and organ systems) …
single biological scale and also among different scales (eg cells, tissues and organ systems) …
HMDB: the human metabolome database
DS Wishart, D Tzur, C Knox, R Eisner… - Nucleic acids …, 2007 - academic.oup.com
Abstract The Human Metabolome Database (HMDB) is currently the most complete and
comprehensive curated collection of human metabolite and human metabolism data in the …
comprehensive curated collection of human metabolite and human metabolism data in the …