Branching out: mechanisms of dendritic arborization
YN Jan, LY Jan - Nature Reviews Neuroscience, 2010 - nature.com
Type-specific dendrite morphology is a hallmark of the neuron and has important functional
implications in determining what signals a neuron receives and how these signals are …
implications in determining what signals a neuron receives and how these signals are …
Concise review: roles of polycomb group proteins in development and disease: a stem cell perspective
VK Rajasekhar, M Begemann - Stem cells, 2007 - academic.oup.com
The acquisition and maintenance of cell fate are essential for metazoan growth and
development. A strict coordination between genetic and epigenetic programs regulates cell …
development. A strict coordination between genetic and epigenetic programs regulates cell …
Cell type–specific genomics of Drosophila neurons
Many tools are available to analyse genomes but are often challenging to use in a cell type–
specific context. We have developed a method similar to the isolation of nuclei tagged in a …
specific context. We have developed a method similar to the isolation of nuclei tagged in a …
The microRNA bantam functions in epithelial cells to regulate scaling growth of dendrite arbors in drosophila sensory neurons
JZ Parrish, P Xu, CC Kim, LY Jan, YN Jan - Neuron, 2009 - cell.com
In addition to establishing dendritic coverage of the receptive field, neurons need to adjust
their dendritic arbors to match changes of the receptive field. Here, we show that dendrite …
their dendritic arbors to match changes of the receptive field. Here, we show that dendrite …
Neuronal Hippo signaling: From development to diseases
Hippo signaling pathway is a highly conserved and familiar tissue growth regulator, primarily
dealing with cell survival, cell proliferation, and apoptosis. The Yes‐associated protein …
dealing with cell survival, cell proliferation, and apoptosis. The Yes‐associated protein …
Cell-intrinsic drivers of dendrite morphogenesis
The proper formation and morphogenesis of dendrites is fundamental to the establishment
of neural circuits in the brain. Following cell cycle exit and migration, neurons undergo …
of neural circuits in the brain. Following cell cycle exit and migration, neurons undergo …
A tumor suppressor activity of Drosophila Polycomb genes mediated by JAK-STAT signaling
A prevailing paradigm posits that Polycomb Group (PcG) proteins maintain stem cell identity
by repressing differentiation genes, and abundant evidence points to an oncogenic role for …
by repressing differentiation genes, and abundant evidence points to an oncogenic role for …
Molecules and mechanisms of dendrite development in Drosophila
MM Corty, BJ Matthews, WB Grueber - 2009 - journals.biologists.com
Neurons are one of the most morphologically diverse cell types, in large part owing to their
intricate dendrite branching patterns. Dendrites are structures that are specialized to receive …
intricate dendrite branching patterns. Dendrites are structures that are specialized to receive …
The MST/Hippo pathway and cell death: a non-canonical affair
E Fallahi, NA O'Driscoll, D Matallanas - Genes, 2016 - mdpi.com
The MST/Hippo signalling pathway was first described over a decade ago in Drosophila
melanogaster and the core of the pathway is evolutionary conserved in mammals. The …
melanogaster and the core of the pathway is evolutionary conserved in mammals. The …
Herding Hippos: regulating growth in flies and man
Control of cell number requires the coordinate regulation of cell proliferation and cell death.
Studies in both the fly and mouse have identified the Hippo kinase pathway as a key …
Studies in both the fly and mouse have identified the Hippo kinase pathway as a key …