Antimicrobial diterpenes: Recent development from natural sources

P Saha, FI Rahman, F Hussain… - Frontiers in …, 2022 - frontiersin.org
Antimicrobial resistance has been posing an alarming threat to the treatment of infectious
diseases over the years. Ineffectiveness of the currently available synthetic and …

Why natural antioxidants are readily recognized by biological systems? 3D architecture plays a role!

ZQ Liu - Food Chemistry, 2022 - Elsevier
A great deal of investigations has convincingly outlined the correlation of pathogenesis of
various fatal diseases with the damages caused by reactive oxygen species (ROS) in vivo …

Alpha-Glucosidase and Alpha-Amylase Inhibitory Activities of Novel Abietane Diterpenes from Salvia africana-lutea

NGER Etsassala, JA Badmus, TT Waryo, JL Marnewick… - Antioxidants, 2019 - mdpi.com
The re-investigation of a methanolic extract of Salvia africana-lutea collected from the Cape
Floristic Region, South Africa (SA), afforded four new abietane diterpenes, namely 19 …

The Chemistry of Kratom [Mitragyna speciosa]: Updated Characterization Data and Methods to Elucidate Indole and Oxindole Alkaloids

L Flores-Bocanegra, HA Raja, TN Graf… - Journal of natural …, 2020 - ACS Publications
Two separate commercial products of kratom [Mitragyna speciosa (Korth.) Havil. Rubiaceae]
were used to generate reference standards of its indole and oxindole alkaloids. While …

A Review on the Ethnopharmacology and Phytochemistry of the Neotropical Sages (Salvia Subgenus Calosphace; Lamiaceae) Emphasizing Mexican Species

N Ortiz-Mendoza, E Aguirre-Hernández… - Frontiers in …, 2022 - frontiersin.org
Salvia is the most diverse genus within the mint family (Lamiaceae), many of its species are
well-known due to their medicinal and culinary uses. Most of the ethnopharmacological and …

Abietane diterpenoids from Orthosiphon wulfenioides with NLRP3 inflammasome inhibitory activity

WC Tu, YX Zhao, CL Yang, XJ Zhang, XL Li… - Bioorganic …, 2023 - Elsevier
Abstract Wulfenioidones A− K (1–11) were abietane diterpenoids with highly oxidized 6/6/6
aromatic tricyclic skeleton isolated from the whole plant of Orthosiphon wulfenioides, and …

Bi-and tricyclic diterpenoids: Landmarks from a decade (2013–2023) in search of leads against infectious diseases

O Antoniuk, A Maranha, JAR Salvador… - Natural Product …, 2024 - pubs.rsc.org
Covering: 2013 to 2023In an era where antimicrobial resistance severely threatens our
ability to treat infections, the discovery of new drugs that belong to different chemical classes …

Spirodesertols A and B, two highly modified spirocyclic diterpenoids with an unprecedented 6-isopropyl-3 H-spiro [benzofuran-2, 1′-cyclohexane] motif from Salvia …

G Zheng, A Kadir, X Zheng, P Jin, J Liu… - Organic Chemistry …, 2020 - pubs.rsc.org
Two highly modified spirocyclic diterpenoids with an unprecedented 6-isopropyl-3H-spiro
[benzofuran-2, 1′-cyclohexane] motif, spirodesertols A (1) and B (2), four new icetexane …

Antiproliferative abietane quinone diterpenoids from the roots of Salvia deserta

X Zheng, A Kadir, G Zheng, P Jin, D Qin… - Bioorganic …, 2020 - Elsevier
A total of twenty abietane quinone diterpenoids including ten new ones (1–10) were isolated
from the roots extract of Salvia deserta. Their chemical structures were delineated by …

Vibrational circular dichroism absolute configuration of natural products from 2015 to 2019

RE del Río, P Joseph-Nathan - Natural Product …, 2021 - journals.sagepub.com
Although demonstrated in 1975, vibrational circular dichroism (VCD) finally started to
popularize during this century as a reliable tool to determine the absolute configuration (AC) …