Age-related cerebrovascular pathologies, ranging from cerebromicrovascular functional and
structural alterations to large vessel atherosclerosis, promote the genesis of vascular …

Parkinson's disease (PD) is a neurodegenerative disorder that results in the death of
dopaminergic neurons within the substantia nigra pars compacta and the reduction in …

To more closely resemble the structure of natural skin, multi-layered wound dressings have
been developed. Herein, a tri-layer wound dressing was prepared containing a …

Rationale: The pathophysiologic mechanisms of air pollution–associated exacerbation of
cardiovascular events remain incompletely understood. Objective: To assess whether …

Designing multifunctional wound dressings is a prerequisite to prevent infection and
stimulate healing. In this study, a bilayer scaffold (BS) with a top layer (TL) comprising 3D …

Osteoarthritis is the most common joint disease and a global leading cause of pain and
disability. Current treatment is limited to symptom relief, yet there is no disease-modifying …

Cardiovascular disease (CVD) is one of the greatest public health concerns and is the
leading cause of morbidity and mortality in the United States and worldwide. CVD is a broad …

Introduction Parkinson's disease (PD) is the most common movement disorder, and its
prevalence is increasing rapidly worldwide with an ageing population. The UK Biobank is …

PCOS treatment should be based on pathophysiology. High-mobility-group-box-1 (HMGB1)
was shown to increase in PCOS patients as a consequence of reduced cystic-fibrosis …

The purpose of the study was to explore the mechanism by which myocardial ischemia-
reperfusion (I/R) injury-induced exosomes modulate mesenchymal stem cells (MSCs) to …