Multifaceted mitochondria: moving mitochondrial science beyond function and dysfunction

AS Monzel, JA Enríquez, M Picard - Nature metabolism, 2023 - nature.com
Mitochondria have cell-type specific phenotypes, perform dozens of interconnected
functions and undergo dynamic and often reversible physiological recalibrations. Given their …

[HTML][HTML] Mitochondria-mediated oxidative stress during viral infection

J Foo, G Bellot, S Pervaiz, S Alonso - Trends in Microbiology, 2022 - cell.com
Through oxidative phosphorylation, mitochondria play a central role in energy production
and are an important production source of reactive oxygen species (ROS). Not surprisingly …

Magnetic field effects in biology from the perspective of the radical pair mechanism

H Zadeh-Haghighi, C Simon - Journal of the Royal …, 2022 - royalsocietypublishing.org
Hundreds of studies have found that weak magnetic fields can significantly influence various
biological systems. However, the underlying mechanisms behind these phenomena remain …

Mitochondria: It is all about energy

A Casanova, A Wevers, S Navarro-Ledesma… - Frontiers in …, 2023 - frontiersin.org
Mitochondria play a key role in both health and disease. Their function is not limited to
energy production but serves multiple mechanisms varying from iron and calcium …

The role of oxidative stress in skeletal muscle myogenesis and muscle disease

D Lian, MM Chen, H Wu, S Deng, X Hu - Antioxidants, 2022 - mdpi.com
The contractile activity, high oxygen consumption and metabolic rate of skeletal muscle
cause it to continuously produce moderate levels of oxidant species, such as reactive …

Effects of dietary n–3 and n–6 polyunsaturated fatty acids in inflammation and cancerogenesis

KP Liput, A Lepczyński, M Ogłuszka… - International journal of …, 2021 - mdpi.com
The dietary recommendation encourages reducing saturated fatty acids (SFA) in diet and
replacing them with polyunsaturated fatty acids (PUFAs) n–3 (omega–3) and n–6 (omega …

Mitochondrial redox signaling and oxidative stress in kidney diseases

AK Aranda-Rivera, A Cruz-Gregorio, OE Aparicio-Trejo… - Biomolecules, 2021 - mdpi.com
Mitochondria are essential organelles in physiology and kidney diseases, because they
produce cellular energy required to perform their function. During mitochondrial metabolism …

Protective effects of curcumin in cardiovascular diseases—Impact on oxidative stress and mitochondria

FF Cox, A Misiou, A Vierkant, N Ale-Agha, M Grandoch… - Cells, 2022 - mdpi.com
Cardiovascular diseases (CVDs) contribute to a large part of worldwide mortality. Similarly,
two of the major risk factors for these diseases, aging and obesity, are also global problems …

The complex interplay between mitochondria, ROS and entire cellular metabolism

AV Kuznetsov, R Margreiter, MJ Ausserlechner… - Antioxidants, 2022 - mdpi.com
Besides their main function for energy production in form of ATP in processes of oxidative
phosphorylation (OxPhos), mitochondria perform many other important cellular functions …

Regulation and functional role of the electron transport chain supercomplexes

S Cogliati, JL Cabrera-Alarcón… - Biochemical Society …, 2021 - portlandpress.com
Mitochondria are one of the most exhaustively investigated organelles in the cell and most
attention has been paid to the components of the mitochondrial electron transport chain …