Chemotherapy remains as the first-choice treatment option for triple-negative breast cancer
(TNBC). However, the limited tumor penetration and low cellular internalization efficiency of …

Free radical‐based anticancer modality has been widely applied to cancer therapies.
However, it still faces challenges of low delivery efficiency and poor selectivity of free radical …

Compared to photodynamic therapy, sonodynamic therapy (SDT) has received increased
attention due to higher tissue penetrative depth and low side effects. However, the hypoxia …

Bioinspired strategies have recently emerged as novel approaches for designing a
functionalized nanovector with enhanced tumor targeting and therapeutic efficacy. Herein, a …

Nanocarrier antigen-drug delivery system interacts specifically with immune cells and
provides intelligent delivery modes to improve antigen delivery efficiency and facilitate …

The anti‐tumor efficacy of single photodynamic therapy (PDT) and radiotherapy (RT) has
been greatly affected by inadequate tumor uptake of photo/radiation sensitizers, limited laser …

Molecular dynamics simulation is a powerful tool in the study of polymeric systems. Among
various simulation methods, coarse-grained (CG) model is particularly impactful because it …

This study compares two kinds of magnetic microbeads with different surface features and
cell entry pathways, aiming to provide insights into how to program their cell uptake and …

To provide insights into the receptor-mediated endocytosis of virus-like nanoparticles
(VLPs), we carried out a series of in silico dissipative particle dynamics (DPD) simulations …

The internalization of antigens by dendritic cells (DCs) is the initial critical step for vaccines
to activate the immune response; however, the systemic delivery of antigens into DCs is …