Acral lentiginous melanoma: Basic facts, biological characteristics and research perspectives of an understudied disease

P Basurto‐Lozada, C Molina‐Aguilar… - Pigment cell & …, 2021 - Wiley Online Library
Acral lentiginous melanoma is a histological subtype of cutaneous melanoma that occurs in
the glabrous skin of the palms, soles and the nail unit. Although in some countries …

Variations in genetics, biology, and phenotype of cutaneous disorders in skin of color–Part I: Genetic, biologic, and structural differences in skin of color

JB Brown-Korsah, S McKenzie, D Omar… - Journal of the American …, 2022 - Elsevier
Skin of color (SOC) populations include those who identify as Black/African, Hispanic/Latinx,
Asian/Pacific Islander, American Indian/Native Alaskan, Indigenous Australian, Middle …

[HTML][HTML] Genetic alterations in primary acral melanoma and acral melanocytic nevus in Korea: common mutated genes show distinct cytomorphological features

KR Moon, YD Choi, JM Kim, S Jin, MH Shin… - Journal of Investigative …, 2018 - Elsevier
Acral melanoma occurring on the palms, soles, and nails is the most common subtype of
cutaneous melanoma in Asians. Genetic alterations in acral melanoma and acral …

The clinicopathological and survival profiles comparison across primary sites in acral melanoma

X Wei, D Wu, H Li, R Zhang, Y Chen, H Yao… - Annals of surgical …, 2020 - Springer
Background The clinicopathological and survival profiles across primary sites in acral
melanoma (AM) are still controversial and unclear. Methods This is a multi-center …

Prognostic value of ulceration varies across Breslow thicknesses and clinical stages in acral melanoma: a retrospective study

X Wei, D Wu, Y Chen, H Li, R Zhang… - British Journal of …, 2022 - academic.oup.com
Background Ulceration is regarded as an adverse prognostic factor and is used together
with tumour thickness to subcategorize patients with cutaneous melanoma. However, the …

Genetic alterations in primary melanoma in Taiwan

YS Sheen, KT Tan, KP Tse, YH Liao… - British Journal of …, 2020 - academic.oup.com
Background Acral melanoma (AM) is the most common histopathological subtype of
malignant melanoma in Asians. However, differences in the mutational profiles underlying …

Integrative molecular and clinical profiling of acral melanoma links focal amplification of 22q11. 21 to metastasis

F Farshidfar, K Rhrissorrakrai, C Levovitz… - Nature …, 2022 - nature.com
Acral melanoma, the most common melanoma subtype among non-White individuals, is
associated with poor prognosis. However, its key molecular drivers remain obscure. Here …

The clinical significance of KIT mutations in melanoma: a meta-analysis

HZ Gong, HY Zheng, J Li - Melanoma research, 2018 - journals.lww.com
This study aimed to evaluate the association of KIT mutations with clinicopathologic features
of melanomas using a meta-analysis and to identify differences between Asian and White …

More than just acral melanoma: the controversies of defining the disease

SS Bernardes, I Ferreira, DE Elder… - The Journal of …, 2021 - Wiley Online Library
Acral melanoma (AM) is a malignant cutaneous melanocytic tumour specifically located on
the palms, soles, and nail apparatus, which are areas of glabrous (hairless) skin. Acral …

[HTML][HTML] The tumor genetics of acral melanoma: what should a dermatologist know?

BM Tod, JW Schneider, AM Bowcock, WI Visser… - JAAD international, 2020 - Elsevier
Dermatologists stand at the gateway of individualization of classification, treatment, and
outcomes of acral melanoma patients. The acral melanoma genetic landscape differs in vital …