The lymph vascular system parallels the blood vasculature and as one of its key functions
returns liquid and solutes to the bloodstream, including macromolecules that have escaped …

The lymphatic vasculature is essential for the maintenance of normal fluid balance and for
the immune responses, but it is also involved in a variety of diseases. Hypoplasia or …

Although lymphedema is a common clinical condition, treatment for this disabling condition
remains limited and largely ineffective. Recently, it has been reported that overexpression of …

Chronic regional impairments of the lymphatic circulation often lead to striking architectural
abnormalities in the lymphedematous tissues. Lymphedema is a common, disabling disease …

OBJECTIVES: Lymph transportation through the body is partly controlled by the intrinsic
pumping of lymphatic vessels. Although an understanding of this process is important for …

Lymphangiogenesis, the formation of new lymphatic vessels from preexisting ones, is an
important biological process associated with diverse pathologies, such as metastatic …

Background Chronic secondary lymphedema is a well-known complication in oncologic
surgery. Autologous lymph node transplantation, lymphovenous anastomosis, and other …

Since lymphedema rarely develops in the mouse hindlimb, the underlying mechanisms
remain unclear. We herein investigated the resolution of chronic hindlimb lymphedema in …

The monitoring of lymphatic drainage is of great importance, particularly in the context of the
early detection and diagnosis of several diseases. Existing methods of imaging and …

Secondary lymphedema often develops after cancer surgery, and over 250 million patients
suffer from this complication. A major symptom of secondary lymphedema is swelling with …