Perfluoroalkyl substances (PFAS) affect inflammation in lung cells and tissues

J Dragon, M Hoaglund, AR Badireddy… - International Journal of …, 2023 - mdpi.com
Adverse lung outcomes from exposure to per-and polyfluoroalkyl substances (PFAS) are
known; however, the mechanism of action is poorly understood. To explore this, human …

PFHxS exposure and the risk of non-alcoholic fatty liver disease

ZS Ulhaq, WKF Tse - Genes, 2024 - mdpi.com
Perfluorohexanesulfonic acid (PFHxS) is a highly prevalent environmental pollutant, often
considered to be less toxic than other poly-and perfluoroalkyl substances (PFASs). Despite …

Per-and polyfluoroalkyl substances alter innate immune function: evidence and data gaps

DW Phelps, AM Connors, G Ferrero… - Journal of …, 2024 - Taylor & Francis
Per-and polyfluoroalkyl substances (PFASs) are a large class of compounds used in a
variety of processes and consumer products. Their unique chemical properties make them …

Maternal and Neonatal Effects of Maternal Oral Exposure to Perfluoro-2-methoxyacetic Acid (PFMOAA) during Pregnancy and Early Lactation in the Sprague–Dawley …

JM Conley, CS Lambright, N Evans… - Environmental …, 2024 - ACS Publications
Perfluoro-2-methoxyacetic acid (PFMOAA) is a short-chain perfluoroalkyl ether carboxylic
acid that has been detected at high concentrations (∼ 10 μg/L) in drinking water in eastern …

Transcriptome analysis reveals the mechanism of the effect of perfluorocaproic acid exposure on brain injury in Carassius auratus

X Jiao, Z yao Guo, J Sun, C Bi, A Qian, Y Li - Aquatic Toxicology, 2023 - Elsevier
Perfluorocaproic acid (PFHxA) has received much attention as an emerging pollutant linked
to neurological problems in humans and fish. However, the potential mechanism remains …

Cross-species transcriptomics analysis highlights conserved molecular responses to per-and polyfluoroalkyl substances

L Beccacece, F Costa, JP Pascali, FM Giorgi - Toxics, 2023 - mdpi.com
In recent decades, per-and polyfluoroalkyl substances (PFASs) have garnered widespread
public attention due to their persistence in the environment and detrimental effects on the …

[HTML][HTML] Perfluorooctane sulfonate (PFOS), a novel environmental pollutant, induces liver injury in mice by activating hepatocyte ferroptosis

Y Yang, L Xie, Y Zhu, Y Sheng, J Wang, X Zhou… - Ecotoxicology and …, 2023 - Elsevier
Objective We investigated the toxicological mechanism by which perfluorooctane sulfonate
(PFOS) induces liver injury via ferroptosis. Methods Primary mouse hepatocytes were …

Poly-and Perfluoroalkyl Substance (PFAS) Analysis in Environmental Matrices: An Overview of the Extraction and Chromatographic Detection Methods

A Iannone, F Carriera, C Di Fiore, P Avino - Analytica, 2024 - mdpi.com
Per-and polyfluoroalkyl substances (PFASs) are carbon–fluorine compounds with
widespread industrial and domestic use, posing potential toxicological risks to humans and …

Associations between prenatal exposure to per-and polyfluoroalkyl substances and plasma immune molecules in three-year-old children in China

H Huang, X Li, Y Deng, S San, D Qiu, A Xu… - Toxicology and Applied …, 2024 - Elsevier
Background Many studies have reported that prenatal exposure to Per-and Polyfluoroalkyl
Substances (PFASs) can disrupt immune function. However, little is known about the effects …

[HTML][HTML] Prenatal and Childhood Air Pollution Exposure, Cellular Immune Biomarkers, and Brain Connectivity in Early Adolescents

DL Cotter, J Morrel, K Sukumaran… - Brain, Behavior, & …, 2024 - Elsevier
Introduction Ambient air pollution is a neurotoxicant with hypothesized immune-related
mechanisms. Adolescent brain structural and functional connectivity may be especially …