Tissue temperature increases, when oxidative metabolism is boosted. The source of
nutrients and oxygen for this metabolism is the blood. The blood also cools down the tissue …

Key points The ventromedial hypothalamus (VMH) and the central melanocortin system both
play vital roles in regulating energy balance by modulating energy intake and utilization …

Understanding the factors that underlie the physical exercise-induced increase in body core
temperature (TCORE) is essential to developing strategies to counteract hyperthermic …

We investigated whether the magnitude of exercise-induced hyperthermia influences
intestinal permeability and tight junction gene expression. Twenty-nine male Wistar rats …

Thermoregulatory changes may influence the rats' prolonged physical performance and are
commonly evaluated during treadmill running. Therefore, we determined the reliability of …

Different methodological approaches have been used to conduct experiments with rats
subjected to treadmill running. Some experimenters have exposed rats to the treadmill setup …

Skeletal muscle thermogenesis provides a potential avenue for better understanding
metabolic homeostasis and mechanisms underlying energy expenditure. Surprisingly little …

Introduction The determination of fatigue and exhaustion in experimental animals is
complicated by the subjective nature of the measurement. Typically, it requires an observer …

Objective Activity thermogenesis and energy expenditure (EE) are elevated in intrinsically
lean rats (high‐capacity runners [HCR]) and are also stimulated by melanocortin receptor …

Athletes use amphetamines to improve their performance through largely unknown
mechanisms. Considering that body temperature is one of the major determinants of …