Regulation of autophagy of the heart in ischemia and reperfusion
SV Popov, AV Mukhomedzyanov, NS Voronkov… - Apoptosis, 2023 - Springer
Abstract Ischemia/reperfusion (I/R) of the heart leads to increased autophagic flux.
Preconditioning stimulates autophagic flux by AMPK and PI3-kinase activation and mTOR …
Preconditioning stimulates autophagic flux by AMPK and PI3-kinase activation and mTOR …
[HTML][HTML] Potential diagnostic biomarkers: 6 cuproptosis-and ferroptosis-related genes linking immune infiltration in acute myocardial infarction
M Miao, S Cao, Y Tian, D Liu, L Chen, Q Chai… - Genes & …, 2023 - nature.com
The current diagnostic biomarkers of acute myocardial infarction (AMI), troponins, lack
specificity and exist as false positives in other non-cardiac diseases. Previous studies …
specificity and exist as false positives in other non-cardiac diseases. Previous studies …
[HTML][HTML] Newsights of endoplasmic reticulum in hypoxia
L Guan, R Ge, S Ma - Biomedicine & Pharmacotherapy, 2024 - Elsevier
The endoplasmic reticulum (ER) is important to cells because of its essential functions,
including synthesizing three major nutrients and ion transport. When cellular homeostasis is …
including synthesizing three major nutrients and ion transport. When cellular homeostasis is …
Inhibition of endoplasmic reticulum stress through activation of MAPK/ERK signaling pathway attenuates hypoxia-mediated cardiomyocyte damage
H Zou, G Liu - Journal of Receptors and Signal Transduction, 2021 - Taylor & Francis
The pathogenesis of post-infarction ischemia-induced myocardial damage is related to
hypoxia-mediated cardiomyocyte damage. In the present study, we explored the roles of …
hypoxia-mediated cardiomyocyte damage. In the present study, we explored the roles of …
Epigenetic signature of human immune aging in the GESTALT study
Age-associated DNA methylation in blood cells convey information on health status.
However, the mechanisms that drive these changes in circulating cells and their …
However, the mechanisms that drive these changes in circulating cells and their …
Lactucaxanthin protects retinal pigment epithelium from hyperglycemia-regulated hypoxia/ER stress/VEGF pathway mediated angiogenesis in ARPE-19 cell and rat …
Hyperglycemia mediated perturbations in biochemical pathways induce angiogenesis in
diabetic retinopathy (DR) pathogenesis. The present study aimed to investigate the …
diabetic retinopathy (DR) pathogenesis. The present study aimed to investigate the …
Protective role of emodin in rats with post-myocardial infarction heart failure and influence on extracellular signal-regulated kinase pathway
J Liu, L Ning - Bioengineered, 2021 - Taylor & Francis
We aimed to explore the effects of emodin on the energy metabolism of myocardial cells in
rats with post-myocardial infarction (MI) heart failure (HF) and the extracellular signal …
rats with post-myocardial infarction (MI) heart failure (HF) and the extracellular signal …
[HTML][HTML] Effects of chronic hypoxia on the gene expression profile in the embryonic heart in three Chinese indigenous chicken breeds (Gallus gallus)
X Li, AME Abdel-Moneim, Z Hu… - Frontiers in Veterinary …, 2022 - frontiersin.org
Hypoxia exposure (HE) has adverse impacts on the embryonic development of chicken,
whereas the mechanism underlying the response of the heart to HE during embryo …
whereas the mechanism underlying the response of the heart to HE during embryo …
Identification of 6 cuproptosis-and ferroptosis-related genes linking immune infiltration as diagnostic biomarkers for acute myocardial infarction
M Zheng, M Miao, S Cao, Y Tian, D Liu, L Chen, Q Chai… - 2023 - researchsquare.com
The current diagnostic biomarkers of acute myocardial infarction (AMI), troponins, lack
specificity and exist as false positives in other non-cardiac diseases. Previous studies …
specificity and exist as false positives in other non-cardiac diseases. Previous studies …