[HTML][HTML] Obesity and type 2 diabetes mellitus: connections in epidemiology, pathogenesis, and treatments

R Ruze, T Liu, X Zou, J Song, Y Chen, R Xu… - Frontiers in …, 2023 - frontiersin.org
The prevalence of obesity and diabetes mellitus (DM) has been consistently increasing
worldwide. Sharing powerful genetic and environmental features in their pathogenesis …

[HTML][HTML] The role of selenium in type-2 diabetes mellitus and its metabolic comorbidities

H Steinbrenner, LH Duntas, MP Rayman - Redox biology, 2022 - Elsevier
This review addresses the role of the essential trace element, selenium, in type-2 diabetes
mellitus (T2DM) and its metabolic co-morbidities, ie, metabolic syndrome, obesity and non …

[HTML][HTML] The role of oxidative stress in pancreatic β cell dysfunction in diabetes

N Eguchi, ND Vaziri, DC Dafoe, H Ichii - International journal of molecular …, 2021 - mdpi.com
Diabetes is a chronic metabolic disorder characterized by inappropriately elevated glucose
levels as a result of impaired pancreatic β cell function and insulin resistance. Extensive …

Chronic tissue inflammation and metabolic disease

YS Lee, J Olefsky - Genes & development, 2021 - genesdev.cshlp.org
Obesity is the most common cause of insulin resistance, and the current obesity epidemic is
driving a parallel rise in the incidence of T2DM. It is now widely recognized that chronic …

Implicating the effect of ketogenic diet as a preventive measure to obesity and diabetes mellitus

S Kumar, T Behl, M Sachdeva, A Sehgal, S Kumari… - Life sciences, 2021 - Elsevier
Obesity and diabetes are the two major metabolic complications linked with bad eating
habits and the sedentary (lazy) lifestyle. In the worst-case situation, metabolic problems are …

Inadequate β-cell mass is essential for the pathogenesis of type 2 diabetes

GC Weir, J Gaglia, S Bonner-Weir - The lancet Diabetes & …, 2020 - thelancet.com
For patients with type 1 diabetes, it is accepted among the scientific community that there is
a marked reduction in β-cell mass; however, with type 2 diabetes, there is disagreement as …

[HTML][HTML] An immediate and long-term complication of COVID-19 may be type 2 diabetes mellitus: the central role of β-cell dysfunction, apoptosis and exploration of …

MR Hayden - Cells, 2020 - mdpi.com
The novel coronavirus disease 2019 (COVID-19) caused by the severe acute respiratory
syndrome coronavirus-2 (SARS-CoV-2) was declared a pandemic by the WHO on 19 March …

[HTML][HTML] Expression of miRNA-29 in pancreatic β cells promotes inflammation and diabetes via TRAF3

Y Sun, Y Zhou, Y Shi, Y Zhang, K Liu, R Liang, P Sun… - Cell reports, 2021 - cell.com
Type 2 diabetes mellitus (T2DM) is recognized as a chronic, low-grade inflammatory
disease characterized by insulin resistance and pancreatic β cell dysfunction; however, the …

Antioxidant, Antidiabetic, and Antibacterial Potentials and Chemical Composition of Salvia officinalis and Mentha suaveolens Grown Wild in Morocco

SH Al-Mijalli, H Assaggaf, A Qasem… - Advances in …, 2022 - Wiley Online Library
This work evaluated in vitro antioxidant, antidiabetic, and antibacterial properties of Salvia
officinalis (S. officinalis) and Mentha suaveolens (M. suaveolens) essential oils (EO). The …

Linoleic acid and the regulation of glucose homeostasis: A review of the evidence

JS Hamilton, EL Klett - Prostaglandins, Leukotrienes and Essential Fatty …, 2021 - Elsevier
The consumption of linoleic acid (LA, ω-6 18: 2), the most common ω-6 polyunsaturated fatty
acid (PUFA) in the Modern Western diet (MWD), has significantly increased over the last …