As key organelles involved in cellular metabolism, mitochondria frequently undergo
adaptive changes in morphology, components and functions in response to various …

According to the 'multiple‐hit'hypothesis, several factors can act simultaneously in
nonalcoholic fatty liver disease (NAFLD) progression. Increased nitro‐oxidative (nitroso …

Background & Aims The pathogenesis of liver fibrosis requires activation of hepatic stellate
cells (HSCs); once activated, HSCs lose intracellular fatty acids but the role of fatty acid …

Carnitine Palmitoyl-Transferase1A (CPT1A) is the rate-limiting enzyme in the fatty acid β-
oxidation, and its deficiency or abnormal regulation can result in diseases like metabolic …

Increased fructose intake from sugar-sweetened beverages and highly processed sweets is
a well-recognized risk factor for the development of obesity and its complications. Fructose …

Non-alcoholic fatty liver disease (NAFLD) is the most prevalent chronic liver disease, and is
related to fatal and non-fatal liver, metabolic, and cardiovascular complications. Its non …

Nonalcoholic fatty liver disease (NAFLD), characterized by ectopic fat accumulation in
hepatocytes, is closely linked to insulin resistance and is the most frequent complication of …

The world is experiencing reflections of the intersection of two pandemics: Obesity and
coronavirus disease 2019. The prevalence of obesity has tripled since 1975 worldwide …

Metabolic dysfunction-associated steatotic liver disease (MASLD), formerly defined as non-
alcoholic fatty liver disease (NAFLD), is a disorder marked by the excessive deposition of …

Cancer cells must maintain metabolic homeostasis under a wide range of conditions and
meet their own energy needs in order to survive and reproduce. In addition to glycolysis …